MmuEX6100021 @ mm10
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28665008-28671044:+
Coord C1 exon
chr2:28665008-28665162
Coord A exon
chr2:28665556-28665629
Coord C2 exon
chr2:28670869-28671044
Length
74 bp
Sequences
Splice sites
3' ss Seq
GTCAACCCAAACTCTTCTAGCCA
3' ss Score
3.63
5' ss Seq
AAGGTACAA
5' ss Score
6.82
Exon sequences
Seq C1 exon
GCCATGTGACAGAAGTGTACCTGGTCCATCTTCATGCCAGTGTTTATGCCCTCTTTCACCGCCTTTATGGGATGTACCCATGTAACTTCGTCTCCTTCCTGCGCTCTCACTACAGTATGAAGGAAAACGTGGAGACTTTTGAAGAAGTGGTCAAG
Seq A exon
CCAATGATGGAGCATGTGCGAATTCACCCGGAATTAGTGACTGGATCCAAGGACCATGAACTGGACCCTCGAAG
Seq C2 exon
GTGGAAGACATTAGAAACTCATGATGTTGTAATAGAGTGTGCCAAAATCTCTCTGGACCCTACAGAAGCCTCGTATGAAGATGGCTATTCTGTGTCACACCAGCTCTCTGCTTGCTTCCCTTACCGTTCAGCTGATGTCACCACCAGCCCTTATGTGGACACACAGAATAGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.120 C2=0.163
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(11.2=100)
A:
PF043887=Hamartin=FE(3.4=100)
C2:
PF043887=Hamartin=FE(13.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCTGCGCTCTCACTACAGT
R:
AGAGAGCTGGTGTGACACAGA
Band lengths:
169-243
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types