DreINT0101090 @ danRer10
Intron Retention
Gene
ENSDARG00000044632 | myo7ab
Description
myosin VIIAb [Source:ZFIN;Acc:ZDB-GENE-091110-4]
Coordinates
chr21:22260040-22260604:+
Coord C1 exon
chr21:22260040-22260230
Coord A exon
chr21:22260231-22260479
Coord C2 exon
chr21:22260480-22260604
Length
249 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
TCTGTTTGTGTTTCTTGCAGTCA
3' ss Score
10.13
Exon sequences
Seq C1 exon
CTGGGCAAGATGCTTCGTTCCTGAGATTCTCAAAGGGAGATCTGATCTTTCTGGATGAGCACACTGGAGAACAGGTCCTGACTTCAGGCTGGGCTCATGGGGTCAATGACCGAACCAAGAAGAGAGGAGACTTTCCTGCGGACAATGTCTATGTGCTGCCCACCATCACCAGGCCACAGTATGATATTGTG
Seq A exon
GTGAGTGGGCTTTCATCCAATACATTCCTTGTACATTGTCAGAAAACAAAAAAATGGACTTATGTAGGAATTTTCACTTTTTTAATCACCAATTTGTAAACAGCATGTGGGAAACCAAACCTTTTCCAACTTTTAGACTGTTTTGCAGGGAAAATTAAAAAAGAAAACAATGTTTACATATGTGCAACAGGCTGCATTTGGTTTTGGCTCATGAAATGAATATTTAGCTTCTGTTTGTGTTTCTTGCAG
Seq C2 exon
TCATTGATCATCATGTCTCCAGACCAGCGTAAGGACTCTGTAAATTTGTCCCAGCAGAATCTGCTGGACAGTGGGGAGAAAGTCCAGCCGTACACTTTAGAGGAGTTCTCCTACGATCACTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000044632:ENSDART00000148019:33
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.062 A=NA C2=0.117
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PD(92.0=71.9)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAAGATGCTTCGTTCCTGA
R:
TCCTCTAAAGTGTACGGCTGGA
Band lengths:
292-541
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]