GgaEX0007174 @ galGal3
Exon Skipping
Gene
ENSGALG00000005206 | ACSL3
Description
NA
Coordinates
chr9:9155524-9159165:+
Coord C1 exon
chr9:9155524-9155633
Coord A exon
chr9:9157330-9157468
Coord C2 exon
chr9:9159015-9159165
Length
139 bp
Sequences
Splice sites
3' ss Seq
TGATGTTTGAATTTCTACAGGAA
3' ss Score
8.35
5' ss Seq
GTGGTAGGT
5' ss Score
7.23
Exon sequences
Seq C1 exon
TTGTTACTCTGTATGCTACCCTAGGAGGTGCAGCAATAGTACATGGGCTAAACGAAACAGAGGTGACCACCATCATTACTAGTAAAGAACTGATGCAAACAAAACTAAAG
Seq A exon
GAAATTGTTTCTCAAATTCCACGGCTGCGACATATTATTACAGTGGATGGCAAACCAACAACATGGTCAGAATTTCCCAAGGGTGTCATTGTTCACACTATGGCTTCTGTGCAAGCTATGGGAGCCAAGGCAGATAGTG
Seq C2 exon
GAAACAAACAGCAAGCCAGGCCTGTACCCTCCGATATTGCAGTGATCATGTACACAAGTGGATCCACAGGAATTCCCAAAGGAGTCATGATCTCCCACTGCAACATAATTGCTGGTATAACTGGAATGGCTGAAAGAATTCCAAATCTGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000005206-'2-3,'2-2,3-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.043 C2=0.078
Domain overlap (PFAM):
C1:
PF0050123=AMP-binding=FE(7.5=100)
A:
PF0050123=AMP-binding=FE(9.6=100)
C2:
PF0050123=AMP-binding=FE(10.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGCTACCCTAGGAGGTGCAG
R:
TTGGAATTCTTTCAGCCATTCCA
Band lengths:
242-381
Functional annotations
There are 1 annotated functions for this event
PMID: 20429931
[Inferred from paralogous MUTEX event in ASCL6]. Isoforms with different fatty acid Gate-domain motifs (by inclusion of mutually exclusive exons) have different activity and the form lacking this domain, isoform 3 (including no exon), showed no detectable activity.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]