GgaEX6014689 @ galGal4
Exon Skipping
Gene
ENSGALG00000008966 | FBXW5
Description
F-box/WD repeat-containing protein 5 [Source:RefSeq peptide;Acc:NP_001025865]
Coordinates
chr17:519412-521449:+
Coord C1 exon
chr17:519412-519569
Coord A exon
chr17:520169-520343
Coord C2 exon
chr17:521301-521449
Length
175 bp
Sequences
Splice sites
3' ss Seq
GTTTGTTCATCTGCCTGTAGATC
3' ss Score
8.47
5' ss Seq
TGGGTAAAT
5' ss Score
4.69
Exon sequences
Seq C1 exon
CTGCTGTCTCCTGGTATGATGAGTTCCAGAGGCTCTACGACACCATCCCTTGCATTGAAGTGCAGGCCCTGAAGGAGCACAATGACCAGGTGTTGCACCTCAGCTTCTCTCACTCGGGCTGTTTGTTTGCATCGTGCTCCAAAGACTGTACTGTTAAG
Seq A exon
ATCTGGAGCAATGAGTTGGACATCTCCCTGCAGCACAGCTCCAACATGAGGCCGTACAACTGGAGCTACACACAGTTCTCCCAGTTCAACTCCGATGACTCCCTCCTTCTGGTATCAGGTGTCTTTGTGGGGCCTCACAACTCCTCATCAGGAGAGATTGCCGTAATCAGCATGG
Seq C2 exon
AGAACTTCACACTGCTTTCCAGAGTGAGGAATAAACCTTATGATGTATTTGGCTGTTGGCTGAATGAAACCAACTTAATATCTGGCAATCTGCATCGGATTGGGCGTATAACCTCCTGTTCTGTGCTGTGGCTGAACAACGCTTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000008966-'6-8,'6-4,11-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PU(89.7=66.0)
A:
PF0040027=WD40=PD(5.1=3.4)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACACCATCCCTTGCATTGA
R:
TTCAGCCACAGCACAGAACAG
Band lengths:
257-432
Functional annotations
There are 1 annotated functions for this event
PMID: 21725316
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, protein kinase assay, western blot. ELM ID: ELMI003387; ELM sequence: KDDSLLL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]