BtaEX6047650 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000010515 | FBXW5
Description
F-box and WD repeat domain containing 5 [Source:HGNC Symbol;Acc:HGNC:13613]
Coordinates
chr11:106288659-106289534:+
Coord C1 exon
chr11:106288659-106288816
Coord A exon
chr11:106289088-106289262
Coord C2 exon
chr11:106289386-106289534
Length
175 bp
Sequences
Splice sites
3' ss Seq
GCTGGGCGCCCCACACGCAGATT
3' ss Score
4.66
5' ss Seq
TAGGTAAGA
5' ss Score
9.14
Exon sequences
Seq C1 exon
CGGCCACGTCCTGGTTCGAGGAGTTCCGCCGCCTCTATGACGCAGTGCCCTGCGTGGAGGTGCAGACGCTCCGGGAGCACACCGACCAAGTCCTGCACCTCAGCTTCTCCCACTCAGGCTACCAGTTTGCTTCCTGCTCCAAGGACTGCACAGTGAAG
Seq A exon
ATTTGGAACAACGACCCGACCATCTCGCTACTGCACAGCGCGGACATGCGGCCCTACAACTGGAGCTACACCCAGTTCTCCCAGTTTAACCAGGACGACTCGCTGCTGCTGGCGTCTGGGGTGTTCCTAGGGCCCCACAACTCCTCCTCAGGCGAGATCGCGGTCATCAGCCTAG
Seq C2 exon
ACACCTTTGCCCTGCTGTCCCGGGTCCGCAACAAGCCCTACGACGTGTTTGGCTGCTGGCTCACCGACACCAGCTTGATCTCGGGGAACCTGCACCGCATCGGGGACATCACGTCCTGCTCAGTGCTCTGGCTCAACAACGCCTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000010515-'6-11,'6-7,7-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PU(89.7=66.0)
A:
PF0040027=WD40=PD(5.1=3.4)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTCCTGGTTCGAGGAGTTC
R:
AGGTTCCCCGAGATCAAGCTG
Band lengths:
244-419
Functional annotations
There are 1 annotated functions for this event
PMID: 21725316
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation, protein kinase assay, western blot. ELM ID: ELMI003387; ELM sequence: KDDSLLL; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]