GgaEX6028098 @ galGal4
Exon Skipping
Gene
ENSGALG00000003357 | FKBP8
Description
peptidyl-prolyl cis-trans isomerase FKBP8 [Source:RefSeq peptide;Acc:NP_001241668]
Coordinates
chr28:3660483-3661363:+
Coord C1 exon
chr28:3660483-3660535
Coord A exon
chr28:3660758-3661060
Coord C2 exon
chr28:3661194-3661363
Length
303 bp
Sequences
Splice sites
3' ss Seq
ACTGTTCCTCTCTCCCGCAGGTC
3' ss Score
14.24
5' ss Seq
TGGGTGAGA
5' ss Score
6.04
Exon sequences
Seq C1 exon
GGGGGGCGCGCGGCGGCCGTTGCTAGGGGGAGTCCCGGCGCGTGACGGGGACG
Seq A exon
GTCGCTACTCTCCCTGCTCTGCCACGATGGCTTCCAGCGGAGAGGAGATGAGCAGCGGCTCCCCGGGCCGGGCAGGCAGCGACACCGAACCGCCCGGTCCGGAACCGGCTGCGACCTGCGCCGCTCAGCTGGACGGTGCAGAGGATTTCGAGGTTCTGGAGGAGGATGAGGACGACCTGAGCGAGCTGCCACCGCTGGAGGACGTGGGACGGGCACGGGGACCACTGCGGGAGGACGCCCAGTCCTCAGAGCAAGGCCCGGGGGAAGCAGCTGAGGACCCCCAGGAATGGCTCGATGTCTTGG
Seq C2 exon
GGAGCGGCTTGCTTAAGAAGAAGACACTCGTGCCAGGTCAGGGCGTGGAGAGCCGCCCCCGCAAGGGCCAGGAGGTGACTGTCCGTCTGAGGGCCACGCTGGAGGATGGCAATGTGGTGGAGGAGAACCCCAGCCTCACCTTTACCCTGGGAGACTGCGATGTATTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003357-'7-1,'7-0,13-1=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.978 C2=0.491
Domain overlap (PFAM):
C1:
NA
A:
NO
C2:
PF0025423=FKBP_C=PU(45.5=70.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGTTGCTAGGGGGAGTCC
R:
TGCAATACATCGCAGTCTCCC
Band lengths:
206-509
Functional annotations
There are 2 annotated functions for this event
PMID: 19546213
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: affinity chromatography technology, anti tag coimmunoprecipitation, colocalization, competition binding, detection by mass spectrometry, fluorescence polarization spectroscopy, fluorescent resonance energy transfer, glutathione s tranferase tag, isothermal titration calorimetry, mutation analysis, protein array, pull down, subcellular preparation. ELM ID: ELMI002479; ELM sequence: LPPLE; Overlap: FULL
PMID: 23413029
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: affinity chromatography technology, anti tag coimmunoprecipitation, colocalization, competition binding, detection by mass spectrometry, fluorescence polarization spectroscopy, fluorescent resonance energy transfer, glutathione s tranferase tag, isothermal titration calorimetry, mutation analysis, protein array, pull down, subcellular preparation. ELM ID: ELMI002479; ELM sequence: LPPLE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]