HsaEX0003066 @ hg38
Exon Skipping
Gene
ENSG00000204305 | AGER
Description
advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320]
Coordinates
chr6:32181524-32182931:-
Coord C1 exon
chr6:32182568-32182931
Coord A exon
chr6:32182247-32182388
Coord C2 exon
chr6:32181524-32181632
Length
142 bp
Sequences
Splice sites
3' ss Seq
CTCTCCCCTTCCCCCACCAGGGT
3' ss Score
11.16
5' ss Seq
TCGGTGAGA
5' ss Score
8.51
Exon sequences
Seq C1 exon
GATCCCCGTCCCACCTTCTCCTGTAGCTTCAGCCCAGGCCTTCCCCGACACCGGGCCTTGCGCACAGCCCCCATCCAGCCCCGTGTCTGGGGTGAGCATAGGTGGGGAGGGCCCCAAGCTCACGTGAGCACGTTCTGGAAGTCTGACCCTTAGGGAAAGAGGGAGTCAAGCCCATGGCCACTGGGATCACTCACAAGTGTAACTCTCCACCTCAAAACCCTTCCAACTCCCAGAGCCTGTGCCTCTGGAGGAGGTCCAATTGGTGGTGGAGCCAGAAGGTGGAGCAGTAGCTCCTGGTGGAACCGTAACCCTGACCTGTGAAGTCCCTGCCCAGCCCTCTCCTCAAATCCACTGGATGAAGGAT
Seq A exon
GGTGTGCCCTTGCCCCTTCCCCCCAGCCCTGTGCTGATCCTCCCTGAGATAGGGCCTCAGGACCAGGGAACCTACAGCTGTGTGGCCACCCATTCCAGCCACGGGCCCCAGGAAAGCCGTGCTGTCAGCATCAGCATCATCG
Seq C2 exon
AACCAGGCGAGGAGGGGCCAACTGCAGGTGAGGGGTTTGATAAAGTCAGGGAAGCAGAAGATAGCCCCCAACACATGTGACTGGGGGGATGGTCAACAAGAAAGGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204305-'14-15,'14-12,16-15
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.726 A=0.736 C2=0.995
Domain overlap (PFAM):
C1:
PF138951=Ig_2=PU(44.0=84.1)
A:
PF138951=Ig_2=PD(91.8=93.8),PF066977=DUF1191=PU(27.7=64.6)
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACTGGGATCACTCACAAG
R:
GGGGCTATCTTCTGCTTCCCT
Band lengths:
256-398
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development