HsaEX0007947 @ hg19
Exon Skipping
Gene
ENSG00000186716 | BCR
Description
breakpoint cluster region [Source:HGNC Symbol;Acc:1014]
Coordinates
chr22:23655074-23656901:+
Coord C1 exon
chr22:23655074-23655208
Coord A exon
chr22:23656155-23656260
Coord C2 exon
chr22:23656739-23656901
Length
106 bp
Sequences
Splice sites
3' ss Seq
TAACCCACCGCCTTCTGCAGCTC
3' ss Score
6.24
5' ss Seq
AAGGTAGCC
5' ss Score
7.58
Exon sequences
Seq C1 exon
ATAACAAGGACGTGTCGGTGATGATGAGCGAGATGGACGTGAACGCCATCGCAGGCACGCTGAAGCTGTACTTCCGTGAGCTGCCCGAGCCCCTCTTCACTGACGAGTTCTACCCCAACTTCGCAGAGGGCATCG
Seq A exon
CTCTTTCAGACCCGGTTGCAAAGGAGAGCTGCATGCTCAACCTGCTGCTGTCCCTGCCGGAGGCCAACCTGCTCACCTTCCTTTTCCTTCTGGACCACCTGAAAAG
Seq C2 exon
GGTGGCAGAGAAGGAGGCAGTCAATAAGATGTCCCTGCACAACCTCGCCACGGTCTTTGGCCCCACGCTGCTCCGGCCCTCCGAGAAGGAGAGCAAGCTCCCTGCCAACCCCAGCCAGCCTATCACCATGACTGACAGCTGGTCCTTGGAGGTCATGTCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716-'44-52,'44-51,46-52
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.164
Domain overlap (PFAM):
C1:
PF0062022=RhoGAP=FE(29.4=100)
A:
PF0062022=RhoGAP=FE(22.9=100)
C2:
PF0062022=RhoGAP=PD(20.9=58.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGTGATGATGAGCGAGATGG
R:
AGTCATGGTGATAGGCTGGCT
Band lengths:
253-359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)