Special

HsaEX0009861 @ hg38

Exon Skipping

Gene
ENSG00000134779 | TPGS2
Description
tubulin polyglutamylase complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:24561]
Coordinates
chr18:36800198-36807934:-
Coord C1 exon
chr18:36807847-36807934
Coord A exon
chr18:36805374-36805502
Coord C2 exon
chr18:36800198-36800311
Length
129 bp
Sequences
Splice sites
3' ss Seq
CTTAACGCATGTTCCCCTAGAGC
3' ss Score
7.98
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
AAGAATAACTGTGTGATGCCTGAAGATGTGAAGAACTTTTACCTGATGACCAATGGCTTCCACATGACATGGAGTGTGAAGCTGGATG
Seq A exon
AGCACATCATTCCACTGGGAAGCATGGCAATTAACAGCATCTCAAAACTGACTCAGCTCACCCAGTCTTCCATGTATTCACTTCCTAATGCACCCACTCTGGCAGACCTGGAGGACGATACACATGAAG
Seq C2 exon
CCAGTGATGATCAGCCAGAGAAGCCTCACTTTGACTCTCGCAGTGTGATATTTGAGCTGGATTCATGCAATGGCAGTGGGAAAGTTTGCCTTGTCTACAAAAGTGGGAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134779-'14-19,'14-14,17-19
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.195 C2=0.145
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSP00000464780





     
                   









    
Main Skipping Isoform:
ENSP00000372530





     
      









    
Other Inclusion Isoforms:
ENSP00000335144, ENSP00000465551, ENSP00000466973, ENSP00000467204, ENSP00000467392, ENSP00000468292, ENSP00000478553, ENSP00000484407
          









    
Other Skipping Isoforms:
ENSP00000482262
  



Associated events






Other assemblies


hg19




Conservation


Mouse
(mm10)
chr18:25149114-25149242 
HIGH PSI
MmuEX0002038
(Tpgs2)
Mouse
(mm9)
chr18:25307615-25307743 
HIGH PSI
MmuEX0002038
(5730494M16Rik)
Rat
(rn6)
chr18:17349866-17349993 
HIGH PSI
RnoEX0092998
(Tpgs2)
Cow
(bosTau6)
chr24:20622042-20622170 
ALTERNATIVE
BtaEX0006358
(C24H18ORF10)
Chicken
(galGal4)
chrZ:6979207-6979328 
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr21:11936529-11936660 
HIGH PSI
DreEX0080787
(tpgs2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AAGAATAACTGTGTGATGCCTGA

				
R: 
CTGGTTTCCCACTTTTGTAGACA

				
Band lengths: 
202-331

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • The Cancer Genome Atlas (TCGA)
  • Genotype-Tissue Expression Project (GTEx)
  • Autistic and control brains
  • Pre-implantation embryo development





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