HsaEX0019116 @ hg19
Exon Skipping
Gene
ENSG00000213047 | DENND1B
Description
DENN/MADD domain containing 1B [Source:HGNC Symbol;Acc:28404]
Coordinates
chr1:197621365-197641286:-
Coord C1 exon
chr1:197641167-197641286
Coord A exon
chr1:197627430-197627499
Coord C2 exon
chr1:197621365-197621445
Length
70 bp
Sequences
Splice sites
3' ss Seq
TTAAAATAATTATTTTACAGTTA
3' ss Score
6.14
5' ss Seq
CTGGTAAGC
5' ss Score
8.69
Exon sequences
Seq C1 exon
GGTGTCTCAGAATCAAGTTGGACAGCACTTTACCTTTGTACTGACAGACATTGAAAGTAAACAGAGATTTGGATTCTGCAGACTGACGTCAGGAGGCACAATTTGTTTATGCATCCTTAG
Seq A exon
TTACCTTCCCTGGTTTGAAGTGTATTACAAGCTTCTAAATACTCTTGCAGATTACTTGGCTAAGGAACTG
Seq C2 exon
GAAAATGATTTGAATGAAACTCTCAGATCACTGTATAACCACCCAGTACCAAAGGCAAATACTCCTGTAAATTTGAGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000213047_MULTIEX1-5/9=4-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0345613=uDENN=PD(48.4=73.2),PF0214116=DENN=PU(3.9=17.1)
A:
PF0214116=DENN=FE(12.8=100)
C2:
PF0214116=DENN=FE(14.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAGAATCAAGTTGGACAGCACT
R:
TTTGCCTTTGGTACTGGGTGG
Band lengths:
173-243
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)