HsaEX0020683 @ hg19
Exon Skipping
Gene
ENSG00000147443 | DOK2
Description
docking protein 2, 56kDa [Source:HGNC Symbol;Acc:2991]
Coordinates
chr8:21769412-21771371:-
Coord C1 exon
chr8:21771050-21771371
Coord A exon
chr8:21769740-21770021
Coord C2 exon
chr8:21769412-21769499
Length
282 bp
Sequences
Splice sites
3' ss Seq
CTCCCACGCCTCTGGCACAGAAA
3' ss Score
5.09
5' ss Seq
CCCGTGAGT
5' ss Score
8.4
Exon sequences
Seq C1 exon
CTAACTCACTGGAAATGCAGGAAGCTTGAGTATAAAACTCACTCAGAAAAAAAAAAAAAAAAGAAAAAAAAGAACACACACTCAGAAGAAACCGCAGGGCCTATCAGCCTGTCGTCATCGAGCAGACTAGAATAGTATAGAAAACCCTAGGCAGAGAGGAAATGAACTTCAGAGAAGGGAAACACACGGCTAAGAAGAGAGAGGCAAGGGCAGGAGTGAAGGAGAGAGCTGAAGCCTGGGGCTCCGAGATGGTCAGAGGATGGGAGACGGGGCAGTGAAACAAGGCTTCTTGTATCTTCAGCAGCAGCAGACGTTTGGAAAG
Seq A exon
AAATGGCGCCGCTTCGGCGCCTCACTGTATGGAGGGTCGGACTGCGCCTTGGCCCGGCTGGAGCTGCAGGAGGGCCCGGAGAAGCCTCGTCGGTGTGAGGCTGCCCGGAAGGTCATCCGCCTCAGTGACTGCCTGCGGGTGGCCGAGGCCGGCGGAGAGGCCAGCAGCCCCCGGGACACCAGTGCCTTCTTCCTGGAGACCAAGGAGCGCCTGTACCTCCTGGCGGCCCCTGCAGCGGAGCGCGGCGACTGGGTGCAGGCCATCTGCCTCCTGGCCTTCCCC
Seq C2 exon
GGGCAGAGGAAGGAGCTCTCGGGGCCAGAGGGAAAGCAGAGCCGGCCCTGCATGGAGGAAAATGAATTGTACAGCAGCGCAGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443_MULTIEX1-1/3=C1-2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.028 C2=0.450
Domain overlap (PFAM):
C1:
PF0016924=PH=PU(14.7=76.2)
A:
PF0016924=PH=PD(83.5=96.8)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTATCAGCCTGTCGTCATC
R:
ACTGCGCTGCTGTACAATTCA
Band lengths:
307-589
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)