HsaEX0020686 @ hg19
Exon Skipping
Gene
ENSG00000146094 | DOK3
Description
docking protein 3 [Source:HGNC Symbol;Acc:24583]
Coordinates
chr5:176932012-176936658:-
Coord C1 exon
chr5:176936341-176936658
Coord A exon
chr5:176935238-176935543
Coord C2 exon
chr5:176932012-176932111
Length
306 bp
Sequences
Splice sites
3' ss Seq
CTCCCGCTCCCCTCCCGCAGAAG
3' ss Score
11.58
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
Exon sequences
Seq C1 exon
CTGTCTCTAGACGGAGGGACGGGAAGTGGCCAGAAGGGGAAGTGTGAGGAGTTCCCGTCCAGCCTGTCATCAGTCTCCCCAGGTCTTGAAGCGGCGGCCCTGCTCCTGGCCGTGACCATGGACCCTCTGGAGACCCCTATCAAGGATGGCATCCTCTACCAGCAGCATGTCAAGTTTGGCAAGGTGGGGACCCCTGGCTGCCAGGCAGCTGCCAAGGACCAACAGTGGGTGGAGAATGCAGCCTCTGCCCCTGCCTCGGACAGCCCAGGCAGACCTGGGAGACTTGGGAAGGGAGTCAGGGTGGAGGATCCCACCCAG
Seq A exon
AAGTGCTGGCGGAAGGTGTGGGCTCTGCTGTATGCAGGAGGCCCATCAGGCGTGGCACGGCTGGAGAGCTGGGAGGTCCGGGATGGTGGCCTGGGAGCAGCGGGTGACAGGTCGGCAGGGCCTGGCCGGCGAGGGGAGCGACGGGTCATCCGCCTGGCTGACTGTGTGTCCGTGCTGCCGGCTGACGGCGAGAGCTGCCCCCGGGACACCGGTGCCTTCCTGCTCACCACCACCGAGCGAAGCCATCTACTGGCTGCTCAGCACCGCCAGGCCTGGATGGGCCCCATCTGCCAGCTGGCCTTCCCG
Seq C2 exon
GGGACAGGGGAGGCCTCCTCAGGATCCACAGATGCCCAGTCTCCCAAGAGGGGCCTGGTCCCCATGGAGGAAAACTCCATCTACTCCTCCTGGCAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146094_CASSETTE1
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.134 A=0.158 C2=0.520
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0217412=IRS=PU(1.6=2.9)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTCATCAGTCTCCCCAGGT
R:
CCTGCCAGGAGGAGTAGATGG
Band lengths:
352-658
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)