HsaEX0022717 @ hg38
Exon Skipping
Gene
ENSG00000135999 | EPC2
Description
enhancer of polycomb homolog 2 [Source:HGNC Symbol;Acc:HGNC:24543]
Coordinates
chr2:148781644-148787568:+
Coord C1 exon
chr2:148781644-148781780
Coord A exon
chr2:148783597-148783756
Coord C2 exon
chr2:148786305-148787568
Length
160 bp
Sequences
Splice sites
3' ss Seq
TAACTTTGTTCATTTTATAGGGC
3' ss Score
8.51
5' ss Seq
CAGGTACAG
5' ss Score
8.68
Exon sequences
Seq C1 exon
TAACAGGGGGTATCACAGAAGAGCAGTTTCAGACACATCAGCAGCAGTTAGTTCAGATGCAAAGGCAGCAACTTGCCCAGCTTCAGCAGAAACAGCAATCTCAGCATTCCTCGCAACAGACACATCCAAAAGCACAG
Seq A exon
GGCTCAAGCACCTCTGACTGTATGTCTAAAACACTTGACTCAGCCAGCGCCCACTTTGCTGCATCTGCAGTGGTCAGTGCACCTGTTCCAAGTCGCAGTGAGGTAGCCAAGGAACAGAACACTGGCCACAACAACATAAACGGTGTTGTCCAGCCTTCAG
Seq C2 exon
AGAGAACCACGAACCAGAAAGATTGGGCTTAAATGGAATAGCAGAGACAACAGTAGCTATGGAAGTGACATAACCTAAAACACGTGGCTCTGACCTGTGCTGATGGTGTGCAGTCATTCATATTCCAGCTGAATGCAAAAGGCAACACTCTGTGGATCACAGAGTGTAACAATGGACCTAAATGGACTATAGTATATTGGATGTTAAATCCATATATGATGTATATTTTGTAAAATTGGGAAAATCACTACCTTGTAAAATAGTTTATTTGTATCATCAATATTATTTCTGTTACTTGAATAGTAGATATTCATCATCATGCTTTTGCACTTGAATTTGCAACTGAATGGATTTTAAAAAATAATTCTTTAATGGGATCATGAGCATGAAATGGGATCCTGCATCACTTGTTTTAACTATTTATTTTGCCATGTTTACATTTTGTATCTTGTAAAAATAAATCCAACTTTGTGTCTAAAAAGTTAAAGATTCATAGCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135999_MULTIEX2-3/4=2-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.935 A=0.815 C2=0.667
Domain overlap (PFAM):
C1:
PF067527=E_Pc_C=PU(18.2=91.3)
A:
PF067527=E_Pc_C=FE(22.9=100)
C2:
PF067527=E_Pc_C=PD(10.0=92.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGGGGTATCACAGAAGAGCA
R:
CACACCATCAGCACAGGTCAG
Band lengths:
243-403
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development