HsaEX0026111 @ hg19
Exon Skipping
Gene
ENSG00000187239 | FNBP1
Description
formin binding protein 1 [Source:HGNC Symbol;Acc:17069]
Coordinates
chr9:132658117-132662826:-
Coord C1 exon
chr9:132662705-132662826
Coord A exon
chr9:132662244-132662380
Coord C2 exon
chr9:132658117-132658275
Length
137 bp
Sequences
Splice sites
3' ss Seq
TGTTTTCCTTTCTTGAGCAGCCC
3' ss Score
7.01
5' ss Seq
AAGGTGACA
5' ss Score
5.19
Exon sequences
Seq C1 exon
GCCTGGCTGGCTGAGGTTGAAGGCCGGCTCCCAGCACGCAGCGAGCAGGCGCGCCGGCAGAGCGGACTGTACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGAG
Seq A exon
CCCAGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGAGTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGGAGCCCCTCCCTGCCATAGGGACGTGCAAAGCTCTCTACACATTTGAAG
Seq C2 exon
GTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACATTGTATGTCATAGAGGAAGACAAAGGCGATGGCTGGACCCGCATTCGGAGAAATGAAGATGAAGAGGGTTATGTCCCCACTTCATATGTCGAAGTCTGTTTGGACAAAAATGCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187239-'26-34,'26-33,29-34
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.809 A=0.760 C2=0.471
Domain overlap (PFAM):
C1:
PF039618=DUF342=PD(22.4=68.3),PF136541=AAA_32=FE(26.7=100),PF143891=Lzipper-MIP1=PD(9.6=19.5),PF0396210=Mnd1=PD(24.0=56.1),PF154561=Uds1=PD(11.1=24.4),PF0043516=Spectrin=PD(11.1=22.0),PF0218511=HR1=PD(5.5=9.8)
A:
PF136541=AAA_32=PD(16.0=51.1),PF146041=SH3_9=PU(11.8=12.8)
C2:
PF146041=SH3_9=PD(86.3=81.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGCTGGCTGAGGTTGAAG
R:
AGTGGGGACATAACCCTCTTCA
Band lengths:
242-379
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
This event
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
PMID: 22153077
This event
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)