GgaEX1025309 @ galGal4
Exon Skipping
Gene
ENSGALG00000004088 | FNBP1
Description
formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]
Coordinates
chr17:5738617-5741331:-
Coord C1 exon
chr17:5741199-5741331
Coord A exon
chr17:5739643-5739779
Coord C2 exon
chr17:5738617-5738775
Length
137 bp
Sequences
Splice sites
3' ss Seq
TATTTTCCTCTCTTGAGCAGCCC
3' ss Score
5.87
5' ss Seq
AAGGTATCG
5' ss Score
8.7
Exon sequences
Seq C1 exon
AGATGCCTTAACAAAGATGAAAGATGTGTATATCAAGAACCCACAGATGGGAGACGCAGCGAGTGTGGACCACAGATTATCAGAACTTGAACAGAACATTGAAAAGCTACGATTAGAAGTGCAGAAATTTGAG
Seq A exon
CCCGGATGGCAGTTACACAGAAGAGCAAAGTCAGGAGACTGAGATGAAAGTACCCGCAACAGATTTTGATGATGAATTTGATGATGAAGAACCACTACCAACCATAGGAACGTGTAAAGCTCTCTATACGTTTGAAG
Seq C2 exon
GTCAGAATGAAGGAACAATTTCTGTAGCAGAAGGAGAAATGCTCTATGTAATAGAAGAAGACAAAGGTGATGGGTGGACACGAATCCGAAGGAACGAAGATGAGGAGGGCTATGTCCCTACGTCTTATGTTGAAGTCTATTTGGACAAAAATGCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000004088_MULTIEX1-2/2=C1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.667 A=0.809 C2=0.537
Domain overlap (PFAM):
C1:
PF122293=PG_binding_4=PD(41.4=91.1),PF154561=Uds1=FE(49.4=100),PF0218511=HR1=FE(71.0=100)
A:
PF146041=SH3_9=PU(11.8=12.8)
C2:
PF146041=SH3_9=PD(86.3=81.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCTTAACAAAGATGAAAGATGTGT
R:
CGTAGGGACATAGCCCTCCTC
Band lengths:
252-389
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]