GgaEX0005472 @ galGal4
Exon Skipping
Gene
ENSGALG00000004088 | FNBP1
Description
formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]
Coordinates
chr17:5739643-5741331:-
Coord C1 exon
chr17:5741199-5741331
Coord A exon
chr17:5740235-5740356
Coord C2 exon
chr17:5739643-5739779
Length
122 bp
Sequences
Splice sites
3' ss Seq
CTGCTGCTTTTCAATGGCAGGGC
3' ss Score
8.09
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
AGATGCCTTAACAAAGATGAAAGATGTGTATATCAAGAACCCACAGATGGGAGACGCAGCGAGTGTGGACCACAGATTATCAGAACTTGAACAGAACATTGAAAAGCTACGATTAGAAGTGCAGAAATTTGAG
Seq A exon
GGCTGGCTGGCCGACGTGGAGGGCAGGTTGCCCGCACGGACTGAGCAGGCCCGGCGGCAGAGTGGGCTGTATGAAGCCCAGAACACATCAGCAGTGAACAGCTGTGCACAGGACCGGGAGAG
Seq C2 exon
CCCGGATGGCAGTTACACAGAAGAGCAAAGTCAGGAGACTGAGATGAAAGTACCCGCAACAGATTTTGATGATGAATTTGATGATGAAGAACCACTACCAACCATAGGAACGTGTAAAGCTCTCTATACGTTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000004088_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.667 A=0.780 C2=0.809
Domain overlap (PFAM):
C1:
PF122293=PG_binding_4=PD(41.4=91.1),PF154561=Uds1=FE(49.4=100),PF0218511=HR1=FE(71.0=100)
A:
PF154561=Uds1=PD(12.4=26.8),PF0218511=HR1=PD(0.1=0.0)
C2:
PF146041=SH3_9=PU(11.8=12.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCTTAACAAAGATGAAAGATGTGT
R:
CACGTTCCTATGGTTGGTAGTGG
Band lengths:
244-366
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]