MmuEX6100323 @ mm9
Exon Skipping
Gene
ENSMUSG00000075415 | Fnbp1
Description
formin binding protein 1 [Source:MGI Symbol;Acc:MGI:109606]
Coordinates
chr2:30891638-30892808:-
Coord C1 exon
chr2:30892676-30892808
Coord A exon
chr2:30892062-30892183
Coord C2 exon
chr2:30891638-30891774
Length
122 bp
Sequences
Splice sites
3' ss Seq
TCTGTGGCTTTTGCTTCCAGGCC
3' ss Score
9.34
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
AGATGCCATCACCAAAATGAAAGATGTGTACCTAAAGAACCCTCAGATGGGAGACCCAGCCAGCCTGGACCAGAAGCTCACCGAAGTCACCCAGAACATAGAGAAACTGCGGCTGGAGGCTCAGAAGTTTGAG
Seq A exon
GCCTGGCTGGCTGAGGTAGAAGGCAGACTCCCAGCTCGGAGTGAGCAGGCACGCCGGCAGAGTGGACTGTATGATGGCCAGACACACCAGACGGTCACTAACTGTGCCCAGGACCGGGAGAG
Seq C2 exon
CCCAGATGGTAGTTACACAGAGGAGCAAAGCCAGGAGAGCGAGCACAAGGTCCTGGCCCCGGATTTCGACGATGAATTTGATGATGAGGAGCCGCTTCCAGCCATAGGGACCTGCAAGGCCCTCTACACATTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075415-'24-26,'24-25,25-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.701 A=0.780 C2=0.783
Domain overlap (PFAM):
C1:
PF104814=CENP-F_N=PD(21.9=71.1),PF143891=Lzipper-MIP1=FE(53.0=100),PF154561=Uds1=FE(54.3=100),PF0218511=HR1=FE(71.0=100)
A:
PF143891=Lzipper-MIP1=PD(10.8=22.0),PF154561=Uds1=PD(12.5=24.4),PF0218511=HR1=PD(0.1=0.0)
C2:
PF0001823=SH3_1=PU(14.6=14.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTACCTAAAGAACCCTCAGATGG
R:
TCAAATGTGTAGAGGGCCTTGC
Band lengths:
243-365
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: