DreEX6048526 @ danRer10
Exon Skipping
Gene
ENSDARG00000036156 | fnbp1a
Description
formin binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-081105-105]
Coordinates
chr8:11543597-11546704:-
Coord C1 exon
chr8:11546572-11546704
Coord A exon
chr8:11546354-11546481
Coord C2 exon
chr8:11543597-11543739
Length
128 bp
Sequences
Splice sites
3' ss Seq
GTCGTTTTGCTTTTTCTCAGGGC
3' ss Score
9.34
5' ss Seq
GAGGTACTT
5' ss Score
7.82
Exon sequences
Seq C1 exon
GGATGCTTTGACTAAAATGAAAGATGTCTACATTAAGAATCCTCACTTGGGCGATCCAGACAGTATAGATCCACGGTTAGAAGAAATCACTCAAAGCTTGGAGAAGTTGCAGTTTGAGGCACATAAATACGAG
Seq A exon
GGCTGGTTGACGGAGGTGGAGAGAAAGTTACTTGAAAAGGGATCAGAGTCCCAAAGAAGACAGAGCAGCCATTTTGATTCGCAGGGCAATACACCTCTTACAAACAACTACGGTCAAAACCGAGAGAG
Seq C2 exon
TCCGGATGGCAGCTACACGGAAGATCCCAGCACAGAGAACACGATGCAGTTCAAATCCCGCAGTACTGAGTTTGATGACGAGTTCGATGAAGAGGAGCCTTTACCCACCATTGGAACATGCAAAGCACTTTATCCATTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000036156-'15-16,'15-15,16-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.789 A=0.791 C2=0.908
Domain overlap (PFAM):
C1:
PF154561=Uds1=FE(53.0=100)
A:
PF154561=Uds1=PD(15.7=30.2)
C2:
PF146041=SH3_9=PU(11.8=12.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGAATCCTCACTTGGGCGAT
R:
CTTCAAATGGATAAAGTGCTTTGCA
Band lengths:
242-370
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]