RnoEX0036513 @ rn6
Exon Skipping
Gene
ENSRNOG00000008258 | Fnbp1
Description
formin binding protein 1 [Source:RGD Symbol;Acc:621350]
Coordinates
chr3:9868308-9869477:-
Coord C1 exon
chr3:9869345-9869477
Coord A exon
chr3:9868710-9868831
Coord C2 exon
chr3:9868308-9868444
Length
122 bp
Sequences
Splice sites
3' ss Seq
TCTGTGGCTTTTGCTCGCAGGCC
3' ss Score
9.59
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
AGACGCCATCACTAAAATGAAAGATGTGTACCTAAAGAACCCTCAGATGGGAGACCCGGCCAGCTTGGACCACAAACTCGCCGAAGTCACCCAGAACATAGAAAAACTGCGGCTGGAGGCTCACAAGTTCGAG
Seq A exon
GCCTGGCTGGCTGAGGTGGAAGGCAGACTCCCAGCTCGGAGTGAGCAGGCACGCCGGCAAAGTGGGCTGTACGACGGCCAGACACACCAGACGGTCACTAACTGCGCCCAGGACCGGGAGAG
Seq C2 exon
CCCAGATGGTAGTTACACAGAAGAGCAAAGCCAGGAGAGCGAGCACAAGGTGCTGGCCACGGACTTCGACGATGAGTTCGACGATGAGGAGCCGCTTCCTGCCATCGGGACCTGCAAGGCCCTCTACACCTTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000008258-'28-26,'28-23,29-26
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.667 A=0.776 C2=0.781
Domain overlap (PFAM):
C1:
PF143891=Lzipper-MIP1=FE(53.0=100),PF154561=Uds1=FE(55.7=100),PF0218511=HR1=FE(71.0=100)
A:
PF143891=Lzipper-MIP1=PD(12.0=23.8),PF154561=Uds1=PD(12.7=23.8),PF0218511=HR1=PD(1.6=2.4)
C2:
PF0001823=SH3_1=PU(12.5=13.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTACCTAAAGAACCCTCAGATGG
R:
CAAAGGTGTAGAGGGCCTTGC
Band lengths:
242-364
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]