DreEX6083061 @ danRer10
Exon Skipping
Gene
ENSDARG00000101028 | fnbp1b
Description
formin binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-091117-6]
Coordinates
chr21:6269976-6270928:+
Coord C1 exon
chr21:6269976-6270108
Coord A exon
chr21:6270197-6270324
Coord C2 exon
chr21:6270768-6270928
Length
128 bp
Sequences
Splice sites
3' ss Seq
TGTGTGTGTGTGTGTTTTAGGGC
3' ss Score
13.27
5' ss Seq
GAGGTACAC
5' ss Score
5.99
Exon sequences
Seq C1 exon
AGATGCTTTGACTAAAATGAAAGAGGTATATATAAAGAACCCACAGATGGGGGATCCCAACAGTGTGGACCCACGGTTAGCAGAGATCGCCCACAACATTGAGAAACTGCAGGTGGAGGCACAGAAATTTGAG
Seq A exon
GGCTGGTTAGCAGAGGTCGAAGGAAGGATGCCGGTAAAGAGTGACACTTCACGGAGGACGAGCACCGTATACGAGACCCAAAACAGCACACCACCCACCAACAACAACTGCGCACAGGATAGAGAGAG
Seq C2 exon
TCCGGATGGCAGTTACACAGAGGAACCGAGTTCTGAGGTCCAGACATCTAATGAATCTAAAGTCCAGCCAGAAACAGCCGAGTCTGGAGATGAGTTTGATGATGCTGAGGAAGACATGCTTCCGACCATCGGCACCTGCAAAGCCCTTTACCCATTCGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000101028-'19-22,'19-20,20-22=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.813 A=0.973 C2=0.925
Domain overlap (PFAM):
C1:
PF154561=Uds1=FE(50.0=100),PF0218511=HR1=FE(63.8=100)
A:
PF154561=Uds1=PD(10.2=20.9),PF0218511=HR1=PD(10.1=16.3)
C2:
PF146041=SH3_9=PU(11.8=10.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGGATCCCAACAGTGTGGA
R:
CGAATGGGTAAAGGGCTTTGC
Band lengths:
242-370
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]