DreEX6083060 @ danRer10
Exon Skipping
Gene
ENSDARG00000101028 | fnbp1b
Description
formin binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-091117-6]
Coordinates
chr21:6270197-6272358:+
Coord C1 exon
chr21:6270197-6270324
Coord A exon
chr21:6270768-6270928
Coord C2 exon
chr21:6272200-6272358
Length
161 bp
Sequences
Splice sites
3' ss Seq
GCGTGTGTGTGATGGAGCAGTCC
3' ss Score
0.71
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
GGCTGGTTAGCAGAGGTCGAAGGAAGGATGCCGGTAAAGAGTGACACTTCACGGAGGACGAGCACCGTATACGAGACCCAAAACAGCACACCACCCACCAACAACAACTGCGCACAGGATAGAGAGAG
Seq A exon
TCCGGATGGCAGTTACACAGAGGAACCGAGTTCTGAGGTCCAGACATCTAATGAATCTAAAGTCCAGCCAGAAACAGCCGAGTCTGGAGATGAGTTTGATGATGCTGAGGAAGACATGCTTCCGACCATCGGCACCTGCAAAGCCCTTTACCCATTCGAAG
Seq C2 exon
GTCATAACGAAGGCACGATTGCAATAACAGAGGGTGAGCTCTTGTACGTAATAGAGGAAGACAAAGGTGACGGATGGACGCGTGTTAGAAGAAATGAAGAGGAGGAAGGTTACGTTCCCACATCCTACGTCGAGGTCTTTCTGGACTCCAACGCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000101028-'20-23,'20-22,21-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.973 A=0.925 C2=0.764
Domain overlap (PFAM):
C1:
PF154561=Uds1=PD(10.2=20.9),PF0218511=HR1=PD(10.1=16.3)
A:
PF146041=SH3_9=PU(11.8=10.9)
C2:
PF146041=SH3_9=PD(86.3=81.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TCGAAGGAAGGATGCCGGTAA
R:
AGACCTCGACGTAGGATGTGG
Band lengths:
250-411
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]