MmuEX6100324 @ mm10
Exon Skipping
Gene
ENSMUSG00000075415 | Fnbp1
Description
formin binding protein 1 [Source:MGI Symbol;Acc:MGI:109606]
Coordinates
chr2:31026206-31036663:-
Coord C1 exon
chr2:31036542-31036663
Coord A exon
chr2:31036118-31036254
Coord C2 exon
chr2:31026206-31033188
Length
137 bp
Sequences
Splice sites
3' ss Seq
TGTCTTCCTCTCTTGAGCAGCCC
3' ss Score
7.07
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
GCCTGGCTGGCTGAGGTAGAAGGCAGACTCCCAGCTCGGAGTGAGCAGGCACGCCGGCAGAGTGGACTGTATGATGGCCAGACACACCAGACGGTCACTAACTGTGCCCAGGACCGGGAGAG
Seq A exon
CCCAGATGGTAGTTACACAGAGGAGCAAAGCCAGGAGAGCGAGCACAAGGTCCTGGCCCCGGATTTCGACGATGAATTTGATGATGAGGAGCCGCTTCCAGCCATAGGGACCTGCAAGGCCCTCTACACATTTGAAG
Seq C2 exon
GTCAGAACGAAGGCACCATTTCCGTAGTTGAAGGAGAGACGCTGAGCGTGATTGAAGAGGACAAAGGCGATGGGTGGACTCGCATCCGCAGAAATGAAGACGAGGAGGGTTACGTCCCCACTTCCTACGTCGAAGTCTATTTAGACAAAAACGCCAAAGGTGCTAAGACTTATATTTAATCCACTTAAAACAAAACAAAAAGCATTGGAGTTGTCTCTCCCCACCACTGTGGCTGTTACAGGCCTTCAAGAGGTCAGCAGAGAGCAAGCGACTCAGACACTCGGGGAACTGGGGGCATCTTGTGCCTGGGTTCGCTTGTCCAACTTGGCTGTGTACAGAACTGCCACCGGCTAGCTTACATCTGTGTCGTTTGAAATCTGATCGGCGTTTCCATTCCATTCAACAAAATGTGTAAATTTAAAATATGATGTATGGTGGTGGCTCGTGCCTATAATCCCAGCTCTCAGGAGGCGGAGCCAGGAGTAGCCAAGTGAGTTTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075415-'62-55,'62-52,63-55
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.779 A=0.787 C2=0.625
Domain overlap (PFAM):
C1:
PF143891=Lzipper-MIP1=PD(10.8=22.0),PF154561=Uds1=PD(12.3=24.4),PF0218511=HR1=PD(0.1=0.0)
A:
PF0001823=SH3_1=PU(14.6=14.9)
C2:
PF0001823=SH3_1=PD(83.3=66.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTGAGGTAGAAGGCAGACT
R:
GACGTAGGAAGTGGGGACGTA
Band lengths:
245-382
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types