BtaEX6046674 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000020313 | FNBP1
Description
Bos taurus formin binding protein 1 (FNBP1), mRNA. [Source:RefSeq mRNA;Acc:NM_001206712]
Coordinates
chr11:100295449-100298446:-
Coord C1 exon
chr11:100298314-100298446
Coord A exon
chr11:100295907-100296028
Coord C2 exon
chr11:100295449-100295588
Length
122 bp
Sequences
Splice sites
3' ss Seq
TTCCTGATTTCTCTTTGCAGGCC
3' ss Score
11.53
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
AGACGCCATCACAAAAATGAAAGATGTCTACCTAAAGAATCCGCAAATGGGAGACCCCACCAGTTTGGATCACAAATTAGCGGAAGTCAGCCAAAATATAGACAAACTGAGACTAGAGACCCAGAAATTCGAG
Seq A exon
GCCTGGCTGGCCGAGGTGGAAGGCCGACTCCCAGCCCGCAGCGACCAGGCCCGTCGGCAGAGTGGGATGTACGAGGCGCAGAACGCCCCCTCCGTCAACAACTGCGCGCAGGATCGGGAGAG
Seq C2 exon
CAGCCCCGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGAGTGAGGTCAAGGTGCTGGCCACAGACTTTGATGACGAGTTTGACGACGAGGAGCCTCTTCCTGCCATAGGGACATGTAAAGCCCTCTACACGTTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000020313-'20-24,'20-23,22-24=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.644 A=0.797 C2=0.736
Domain overlap (PFAM):
C1:
PF154561=Uds1=FE(50.0=100),PF0218511=HR1=FE(66.7=100)
A:
PF154561=Uds1=PD(10.2=22.0),PF0218511=HR1=PD(6.1=9.8)
C2:
PF146041=SH3_9=PU(11.8=12.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGACGCCATCACAAAAATGAAAGA
R:
TATGGCAGGAAGAGGCTCCTC
Band lengths:
242-364
Functional annotations
There are 2 annotated functions for this event
PMID: 14596906
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis, two hybrid, x-ray crystallography. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
PMID: 22153077
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002056; ELM sequence: DRESPDGS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]