HsaEX0028545 @ hg19
Exon Skipping
Gene
ENSG00000161835 | GRASP
Description
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein [Source:HGNC Symbol;Acc:18707]
Coordinates
chr12:52404665-52407564:+
Coord C1 exon
chr12:52404665-52404719
Coord A exon
chr12:52404823-52404925
Coord C2 exon
chr12:52407471-52407564
Length
103 bp
Sequences
Splice sites
3' ss Seq
GGTCCCCTTGTCCATTACAGACT
3' ss Score
7.6
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
GAAAGTGCTGACGTTGGAGAAGGAGGATAACCAGACCTTCGGCTTTGAGATCCAG
Seq A exon
ACTTATGGCCTTCACCACCGGGAGGAGCAGCGTGTGGAAATGGTGACCTTTGTCTGCCGAGTTCATGAGTCTAGCCCTGCCCAGCTGGCTGGGCTCACACCAG
Seq C2 exon
GGGACACCATCGCCAGCGTCAATGGCCTGAATGTGGAAGGCATCCGGCATCGAGAGATTGTGGACATCATTAAGGCGTCAGGCAATGTTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000161835_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.526 A=0.114 C2=0.000
Domain overlap (PFAM):
C1:
PF0059519=PDZ=PU(18.4=84.2)
A:
PF0059519=PDZ=PU(36.8=95.5)
C2:
PF0059519=PDZ=FE(35.6=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGCTGACGTTGGAGAAGGA
R:
CTGAGAACATTGCCTGACGCC
Band lengths:
146-249
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)