HsaEX0029889 @ hg19
Exon Skipping
Gene
ENSG00000109758 | HGFAC
Description
HGF activator [Source:HGNC Symbol;Acc:4894]
Coordinates
chr4:3444459-3445888:+
Coord C1 exon
chr4:3444459-3444639
Coord A exon
chr4:3444777-3444873
Coord C2 exon
chr4:3445766-3445888
Length
97 bp
Sequences
Splice sites
3' ss Seq
CTGCCACCCCCTCCCCACAGCAC
3' ss Score
10.59
5' ss Seq
GTGGTGGGT
5' ss Score
4.29
Exon sequences
Seq C1 exon
AACCGTACGGAGTCCCCAGAACCTAATGCCACAGCGACCCCTGCGATCCCCACTATCCTGGTGACCTCTGTGACCTCTGAGACCCCAGCAACAAGTGCTCCAGAGGCAGAGGGACCCCAAAGTGGGGGGCTCCCGCCCCCGCCCAGGGCAGTTCCCTCGAGCAGTAGCCCCCAGGCCCAAG
Seq A exon
CACTCACCGAGGACGGGAGGCCCTGCAGGTTCCCCTTCCGCTACGGGGGCCGCATGCTGCATGCCTGCACTTCGGAGGGCAGTGCACACAGGAAGTG
Seq C2 exon
CTGCCCTGGATCCCTGTGCCTCCGGCCCCTGCCTCAATGGAGGCTCCTGCTCCAATACCCAGGACCCCCAGTCCTATCACTGCAGCTGCCCCCGGGCCTTCACCGGCAAGGACTGCGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109758_MULTIEX1-1/2=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.121 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0004014=fn2=PU(58.5=72.7)
C2:
PF0000822=EGF=WD(100=78.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAGACCCCAGCAACAAGTG
R:
TCCTGGGTATTGGAGCAGGAG
Band lengths:
169-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)