HsaEX0030398 @ hg19
Exon Skipping
Gene
ENSG00000105707 | HPN
Description
hepsin [Source:HGNC Symbol;Acc:5155]
Coordinates
chr19:35551251-35556249:+
Coord C1 exon
chr19:35551251-35551416
Coord A exon
chr19:35551531-35551721
Coord C2 exon
chr19:35556154-35556249
Length
191 bp
Sequences
Splice sites
3' ss Seq
TCCACCCCTTTCCCTGGTAGGCG
3' ss Score
8.85
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
ACTGTGGCCGCAGGAAGCTGCCCGTGGACCGCATCGTGGGAGGCCGGGACACCAGCTTGGGCCGGTGGCCGTGGCAAGTCAGCCTTCGCTATGATGGAGCACACCTCTGTGGGGGATCCCTGCTCTCCGGGGACTGGGTGCTGACAGCCGCCCACTGCTTCCCGGA
Seq A exon
GCGGAACCGGGTCCTGTCCCGATGGCGAGTGTTTGCCGGTGCCGTGGCCCAGGCCTCTCCCCACGGTCTGCAGCTGGGGGTGCAGGCTGTGGTCTACCACGGGGGCTATCTTCCCTTTCGGGACCCCAACAGCGAGGAGAACAGCAACGATATTGCCCTGGTCCACCTCTCCAGTCCCCTGCCCCTCACAG
Seq C2 exon
AATACATCCAGCCTGTGTGCCTCCCAGCTGCCGGCCAGGCCCTGGTGGATGGCAAGATCTGTACCGTGACGGGCTGGGGCAACACGCAGTACTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105707_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF092725=Hepsin-SRCR=PD(6.4=12.5),PF0008921=Trypsin=PU(18.5=78.6)
A:
PF092725=Hepsin-SRCR=PD(27.7=27.7),PF0008921=Trypsin=FE(32.8=100)
C2:
PF0008921=Trypsin=FE(13.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGAAGCTGCCCGTGGA
R:
CATAGTACTGCGTGTTGCCCC
Band lengths:
252-443
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)