HsaEX0030677 @ hg38
Exon Skipping
Gene
ENSG00000149305 | HTR3B
Description
5-hydroxytryptamine receptor 3B [Source:HGNC Symbol;Acc:HGNC:5298]
Coordinates
chr11:113932936-113944755:+
Coord C1 exon
chr11:113932936-113933093
Coord A exon
chr11:113942982-113943192
Coord C2 exon
chr11:113944573-113944755
Length
211 bp
Sequences
Splice sites
3' ss Seq
GACCACTTGTTCCCGGCCAGGTG
3' ss Score
7.75
5' ss Seq
TTGGTAAGC
5' ss Score
8.72
Exon sequences
Seq C1 exon
TGGAAGACGTAGACCTGGCCTTTCTGAGGAGCCCAGAAGACATTCAGCATGACAAAAAGGCGTTTTTGAATGACAGTGAGTGGGAACTTCTATCTGTGTCCTCCACATACAGCATCCTGCAGAGCAGCGCTGGAGGATTTGCACAGATTCAGTTTAAT
Seq A exon
GTGGTGATGCGCAGGCACCCCCTGGTCTATGTCGTGAGTCTGCTGATTCCTAGCATCTTTCTCATGCTGGTGGACCTGGGGAGCTTCTACCTGCCACCCAACTGCCGAGCCAGGATTGTGTTCAAGACCAGTGTGCTGGTGGGCTACACCGTCTTCAGGGTCAACATGTCCAACCAGGTGCCACGGAGTGTAGGGAGCACCCCTCTGATTG
Seq C2 exon
GGCACTTCTTCACCATCTGCATGGCCTTCTTGGTTCTCAGCTTAGCTAAGTCCATCGTGTTGGTCAAATTCCTCCATGATGAGCAGCGTGGTGGACAGGAGCAGCCCTTCTTGTGCCTTCGAGGGGACACCGATGCTGACAGGCCTAGAGTGGAACCCAGGGCCCAACGTGCTGTGGTAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000149305_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.062
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(25.0=100)
A:
PF0293118=Neur_chan_LBD=PD(2.9=8.5),PF0293211=Neur_chan_memb=PU(57.6=80.3)
C2:
PF0293211=Neur_chan_memb=PD(41.4=66.1)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTAGACCTGGCCTTTCTGA
R:
TTCCACTCTAGGCCTGTCAGC
Band lengths:
307-518
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development