HsaEX0032477 @ hg19
Exon Skipping
Gene
ENSG00000115221 | ITGB6
Description
integrin, beta 6 [Source:HGNC Symbol;Acc:6161]
Coordinates
chr2:161051880-161055769:-
Coord C1 exon
chr2:161055690-161055769
Coord A exon
chr2:161052727-161052931
Coord C2 exon
chr2:161051880-161052126
Length
205 bp
Sequences
Splice sites
3' ss Seq
TTTTTCTTTTTCTTTTTTAGAAT
3' ss Score
13.73
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
GTGGCTGTGCCCTGGGAGGTGCAGAAACCTGTGAAGACTGCCTGCTTATTGGACCTCAGTGTGCCTGGTGTGCTCAGGAG
Seq A exon
AATTTTACTCATCCATCTGGAGTTGGCGAAAGGTGTGATACCCCAGCAAACCTTTTAGCTAAAGGATGTCAATTAAACTTCATCGAAAACCCTGTCTCCCAAGTAGAAATACTTAAAAATAAGCCTCTCAGTGTAGGCAGACAGAAAAATAGTTCTGACATTGTTCAGATTGCGCCTCAAAGCTTGATCCTTAAGTTGAGACCAG
Seq C2 exon
GTGGTGCGCAGACTCTGCAGGTGCATGTCCGCCAGACTGAGGACTACCCGGTGGATTTGTATTACCTCATGGACCTCTCCGCCTCCATGGATGACGACCTCAACACAATAAAGGAGCTGGGCTCCCGGCTTTCCAAAGAGATGTCTAAATTAACCAGCAACTTTAGACTGGGCTTCGGATCTTTTGTGGAAAAACCTGTATCCCCTTTTGTGAAAACAACACCAGAAGAAATTGCCAACCCTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115221-'10-13,'10-12,12-13
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.018
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(50.0=92.6),PF0036213=Integrin_beta=PU(9.9=63.0)
A:
PF0143720=PSI=PD(46.0=33.3),PF0036213=Integrin_beta=FE(39.5=100)
C2:
PF0036213=Integrin_beta=PD(23.7=64.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACCTGTGAAGACTGCCTGC
R:
CTGCAAGGGTTGGCAATTTCT
Band lengths:
303-508
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)