HsaEX0032479 @ hg19
Exon Skipping
Gene
ENSG00000115221 | ITGB6
Description
integrin, beta 6 [Source:HGNC Symbol;Acc:6161]
Coordinates
chr2:161052727-161056812:-
Coord C1 exon
chr2:161056514-161056812
Coord A exon
chr2:161055690-161055769
Coord C2 exon
chr2:161052727-161052931
Length
80 bp
Sequences
Splice sites
3' ss Seq
CTTGCTGGGTCTAAACCTAGGTG
3' ss Score
5.61
5' ss Seq
GAGGTAAAA
5' ss Score
7.3
Exon sequences
Seq C1 exon
TTGAAGTTGCTTTTAAACACAGCTTTTCTGCTTTACCTGTCCAGGTAGCCTCTGTTTTCATTTCAGTCTTAATGAAAACTTTCTAACTTATATCTCAAGTTTCTTTTCAAAGCAGTGTAAGTAGTATTTAAAATGTTATACTTCAAGAAAGAAAGACTTTAACGATATTCAGCGTTGGTCTTGTAACGCTGAAGGTAATTCATTTTTTAATCGGTCTGCACAGCAAGAACTGAAACGAATGGGGATTGAACTGCTTTGCCTGTTCTTTCTATTTCTAGGAAGGAATGATCACGTACAAG
Seq A exon
GTGGCTGTGCCCTGGGAGGTGCAGAAACCTGTGAAGACTGCCTGCTTATTGGACCTCAGTGTGCCTGGTGTGCTCAGGAG
Seq C2 exon
AATTTTACTCATCCATCTGGAGTTGGCGAAAGGTGTGATACCCCAGCAAACCTTTTAGCTAAAGGATGTCAATTAAACTTCATCGAAAACCCTGTCTCCCAAGTAGAAATACTTAAAAATAAGCCTCTCAGTGTAGGCAGACAGAAAAATAGTTCTGACATTGTTCAGATTGCGCCTCAAAGCTTGATCCTTAAGTTGAGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115221-'9-12,'9-11,10-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PU(0.7=60.0)
A:
PF0143720=PSI=PU(50.0=92.6),PF0036213=Integrin_beta=PU(9.9=63.0)
C2:
PF0143720=PSI=PD(46.0=33.3),PF0036213=Integrin_beta=FE(39.5=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAATGGGGATTGAACTGCT
R:
ACTTGGGAGACAGGGTTTTCG
Band lengths:
169-249
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)