HsaEX0032479 @ hg38
Exon Skipping
Gene
ENSG00000115221 | ITGB6
Description
integrin subunit beta 6 [Source:HGNC Symbol;Acc:HGNC:6161]
Coordinates
chr2:160196216-160200301:-
Coord C1 exon
chr2:160200003-160200301
Coord A exon
chr2:160199179-160199258
Coord C2 exon
chr2:160196216-160196420
Length
80 bp
Sequences
Splice sites
3' ss Seq
CTTGCTGGGTCTAAACCTAGGTG
3' ss Score
5.61
5' ss Seq
GAGGTAAAA
5' ss Score
7.3
Exon sequences
Seq C1 exon
TTGAAGTTGCTTTTAAACACAGCTTTTCTGCTTTACCTGTCCAGGTAGCCTCTGTTTTCATTTCAGTCTTAATGAAAACTTTCTAACTTATATCTCAAGTTTCTTTTCAAAGCAGTGTAAGTAGTATTTAAAATGTTATACTTCAAGAAAGAAAGACTTTAACGATATTCAGCGTTGGTCTTGTAACGCTGAAGGTAATTCATTTTTTAATCGGTCTGCACAGCAAGAACTGAAACGAATGGGGATTGAACTGCTTTGCCTGTTCTTTCTATTTCTAGGAAGGAATGATCACGTACAAG
Seq A exon
GTGGCTGTGCCCTGGGAGGTGCAGAAACCTGTGAAGACTGCCTGCTTATTGGACCTCAGTGTGCCTGGTGTGCTCAGGAG
Seq C2 exon
AATTTTACTCATCCATCTGGAGTTGGCGAAAGGTGTGATACCCCAGCAAACCTTTTAGCTAAAGGATGTCAATTAAACTTCATCGAAAACCCTGTCTCCCAAGTAGAAATACTTAAAAATAAGCCTCTCAGTGTAGGCAGACAGAAAAATAGTTCTGACATTGTTCAGATTGCGCCTCAAAGCTTGATCCTTAAGTTGAGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115221-'20-23,'20-21,21-23
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PU(0.7=60.0)
A:
PF0036213=Integrin_beta=PU(44.7=63.0)
C2:
PF0036213=Integrin_beta=FE(15.9=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAATGGGGATTGAACTGCT
R:
ACTTGGGAGACAGGGTTTTCG
Band lengths:
169-249
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development