HsaEX0035261 @ hg38
Exon Skipping
Gene
ENSG00000130702 | LAMA5
Description
laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]
Coordinates
chr20:62310178-62310829:-
Coord C1 exon
chr20:62310665-62310829
Coord A exon
chr20:62310419-62310572
Coord C2 exon
chr20:62310178-62310311
Length
154 bp
Sequences
Splice sites
3' ss Seq
TGCCCGGTCTGCTCCTATAGGTG
3' ss Score
10.17
5' ss Seq
TAGGTCTGT
5' ss Score
3.44
Exon sequences
Seq C1 exon
GTCTCCGTGCGCTGGGAGAAGAACCGGATCCTGCTGGTGACGGACGGGGCCCGGGCCTGGAGCCAGGAGGGGCCGCACCGGCAGCACCAGGGGGCAGAGCACCCCCAGCCCCACACCCTCTTTGTGGGCGGCCTCCCGGCCAGCAGCCACAGCTCCAAACTTCCG
Seq A exon
GTGACCGTCGGGTTCAGCGGCTGTGTGAAGAGACTGAGGCTGCACGGGAGGCCCCTGGGGGCCCCCACACGGATGGCAGGGGTCACACCCTGCATCTTGGGCCCCCTGGAGGCGGGCCTGTTCTTCCCAGGCAGCGGGGGAGTTATCACTTTAG
Seq C2 exon
ACCTCCCAGGAGCTACACTGCCTGATGTGGGCCTGGAACTGGAGGTGCGGCCCCTGGCAGTCACCGGACTGATCTTCCACTTGGGCCAGGCCCGGACGCCCCCCTACTTGCAGTTGCAGGTGACCGAGAAGCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130702_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.436 A=0.038 C2=0.000
Domain overlap (PFAM):
C1:
PF0221019=Laminin_G_2=FE(41.5=100)
A:
PF0221019=Laminin_G_2=PD(12.3=30.8)
C2:
PF0221019=Laminin_G_2=PU(23.2=64.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGGAGAAGAACCGGATCCT
R:
CTGGCCCAAGTGGAAGATCAG
Band lengths:
243-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development