HsaEX0038086 @ hg19
Exon Skipping
Gene
ENSG00000204406 | MBD5
Description
methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:20444]
Coordinates
chr2:149220151-149228030:+
Coord C1 exon
chr2:149220151-149220253
Coord A exon
chr2:149221308-149221488
Coord C2 exon
chr2:149225910-149228030
Length
181 bp
Sequences
Splice sites
3' ss Seq
AAAGGCTGTGCTTTTTCCAGGTA
3' ss Score
8.09
5' ss Seq
CAAGTATGT
5' ss Score
7.44
Exon sequences
Seq C1 exon
TCCCAGTGGGTCTTTGTTATCTTGCTTGGAGCAGGTTAAAACATACCTGCTTACTGATGGAACATGCAAGTGTGGCTTGGAATGTCCTCTTATTCTTCCCAAG
Seq A exon
GTATTTAATTTTGATCCTGGAGCTGCTGTGAAACAGAGAACCGCAGAAGATGTTAAGGCAGATGAAGATGTCACAAAGCTATGCATACATAAAAGAAAAATTATTGCAGTGGCCACACTTCATAAAAGCATGGAAGCCCCACATCCTTCTCTGGTGCTCACCAGTCCCGGAGGAGGAACAA
Seq C2 exon
ATGCAACTCCAGTAGTACCTTCTCGGGCAGCAACTCCAAGATCAGTAAGAAATAAGTCTCATGAAGGAATTACAAATTCTGTAATGCCTGAATGTAAGAATCCTTTCAAGTTAATGATTGGATCATCAAATGCCATGGGAAGGCTATATGTACAAGAACTGCCTGGAAGCCAACAACAAGAACTCCACCCTGTCTACCCCCGACAGAGATTGGGCAGCAGTGAACATGGACAGAAATCTCCATTCCGTGGCAGCCATGGAGGCCTGCCCAGCCCAGCGTCATCAGGTTCCCAGATATATGGAGATGGTTCAATCTCTCCAAGGACTGACCCACTTGGAAGTCCTGATGTTTTCACAAGAAGTAATCCTGGTTTTCATGGAGCTCCCAATTCTAGTCCTATTCACCTGAATAGGACTCCTCTTTCTCCACCTTCAGTAATGCTACATGGTTCTCCTGTACAGTCATCCTGTGCAATGGCTGGAAGGACTAATATACCTCTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204406-'25-27,'25-26,26-27
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.328 C2=0.876
Domain overlap (PFAM):
C1:
PF0142914=MBD=FE(50.7=100)
A:
PF0142914=MBD=PD(16.4=18.0)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAACATGCAAGTGTGGCTT
R:
GGGTAGACAGGGTGGAGTTCT
Band lengths:
245-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)