HsaEX0038905 @ hg19
Exon Skipping
Gene
ENSG00000087995 | METTL2A
Description
methyltransferase like 2A [Source:HGNC Symbol;Acc:25755]
Coordinates
chr17:60501246-60518117:+
Coord C1 exon
chr17:60501246-60501373
Coord A exon
chr17:60512593-60512653
Coord C2 exon
chr17:60517978-60518117
Length
61 bp
Sequences
Splice sites
3' ss Seq
GTCTTTTCTGCCCATTTCAGTGA
3' ss Score
9.44
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GTTTCCGGCTCCGGTGTCATGGCCGGCTCCTACCCTGAAGGTGCACCTGCAGTCCTCGCCGATAAGAGGCAGCAGTTCGGAAGCCGGTTCCTGAGAGATCCGGCGCGCGTCTTCCACCACAATGCCTG
Seq A exon
TGACCCAGGACTCTTTGTTTATTGCTGTGATTTTTCTTCCACAGCTATAGAACTGGTCCAG
Seq C2 exon
ACAAATTCAGAATATGATCCTTCTCGGTGTTTTGCCTTTGTTCACGACCTGTGTGATGAAGAGAAGAGTTACCCAGTGCCCAAGGGCAGTCTTGATATTATCATTCTCATATTTGTTCTTTCAGCAATTGTTCCAGACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087995_MULTIEX1-4/4=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.054 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF134891=Methyltransf_23=FE(10.4=100)
C2:
PF134891=Methyltransf_23=FE(23.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCCGGTTCCTGAGAGATCC
R:
TATCAAGACTGCCCTTGGGCA
Band lengths:
145-206
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)