HsaEX0038940 @ hg38
Exon Skipping
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:HGNC:25856]
Coordinates
chr2:171339184-171392197:-
Coord C1 exon
chr2:171392043-171392197
Coord A exon
chr2:171360422-171360513
Coord C2 exon
chr2:171339184-171339554
Length
92 bp
Sequences
Splice sites
3' ss Seq
AGTCTATTTTTTTTTAATAGGGA
3' ss Score
7.37
5' ss Seq
AAGGTAGTC
5' ss Score
5.64
Exon sequences
Seq C1 exon
GTACTGCTTAGGATGAATATGATTTGGAGAAATTCCATTTCTTGTCTAAGGCTAGGAAAGGTGCCACACAGATACCAAAGTGGTTACCACCCAGTGGCCCCTCTGGGATCAAGGATTTTAACTGACCCAGCCAAAGTTTTTGAACACAACATGTG
Seq A exon
GGATCACATGCAGTGGTCTAAGGAAGAAGAAGCAGCAGCCAGAAAAAAAGTAAAAGAAAACTCAGCTGTGCGAGTCCTTCTGGAAGAGCAAG
Seq C2 exon
TTAAGTATGAGAGAGAAGCTAGTAAATACTGGGACACATTTTACAAGATTCATAAGAATAAGTTTTTCAAGGATCGTAATTGGCTGTTGAGGGAATTTCCTGAAATTCTTCCAGTTGATCAAAAACCTGAAGAGAAGGCGAGAGAATCATCATGGGATCATGTAAAAACTAGTGCTACAAATCGTTTCTCAAGAATGCACTGTCCTACTGTGCCTGATGAAAAAAATCATTATGAGAAAAGTTCTGGTTCTTCAGAAGGTCAAAGCAAAACAGAATCTGATTTTTCCAACCTAGACTCTGAAAAACACAAAAAAGGACCTATGGAGACTGGATTGTTTCCTGGTAGCAATGCCACTTTCAGGATACTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600_MULTIEX1-3/10=2-4
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.153 C2=0.447
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF134891=Methyltransf_23=PU(10.4=80.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGACCCAGCCAAAGTTTTTGA
R:
TCTCTCGCCTTCTCTTCAGGT
Band lengths:
180-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development