HsaEX0040459 @ hg38
Exon Skipping
Gene
ENSG00000143033 | MTF2
Description
metal response element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:29535]
Coordinates
chr1:93079238-93114783:+
Coord C1 exon
chr1:93079238-93079531
Coord A exon
chr1:93110545-93110626
Coord C2 exon
chr1:93114688-93114783
Length
82 bp
Sequences
Splice sites
3' ss Seq
AGTATTTCTCTGTATTGCAGATA
3' ss Score
8.74
5' ss Seq
CAGGCAGGT
5' ss Score
2.53
Exon sequences
Seq C1 exon
GCCATTCGGCACCGGAGTCGCTCCGCGCTCCCAGAATGCACCGGCAGTCCGCGGGAAACCAAAATGGCGAGGGGCTGTATTGAAGTGGGCTGTGTTTGAGGCCGGTGTAAGAACGCTCATTCTACCCCCAACCCTTGTCTCCAAGGACCTCGGTTTGTGCGTGCATATGTGCCGGGTACCCGGTGGGGCGGGTGCCCAGTAAGTGCTCGGACTCGCAGGGGAAGCGCCCACGGGGACGGATTGGTTGTTTTTTCCTGTATGAAGCGGTTGGCACCACTGAAGTGACCGAATGAG
Seq A exon
ATAAACATATTGAAACAGAGCTGCTTCATCATATTTGAAGACAGTTCTAAATCCTGGGTTCTCTGGAAGGACATTCAAACAG
Seq C2 exon
GAGCCACTGGAAGTGGGGAAATGGTCTGTACAATATGTCAAGAAGAGTATTCAGAAGCTCCCAATGAAATGGTTATATGTGACAAGTGTGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143033_MULTIEX2-5/5=C1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.385 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF150571=DUF4537=FE(45.0=100)
C2:
PF144461=Prok-RING_1=PU(53.2=96.2),PF0062824=PHD=PU(44.4=92.3)
Main Skipping Isoform:
ENST00000370298fB31217
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCCAAGGACCTCGGTTTGT
R:
GACCATTTCCCCACTTCCAGT
Band lengths:
183-265
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development