HsaEX0042206 @ hg19

Exon Skipping

Gene

ENSG00000072864 | NDE1

Description

nudE nuclear distribution E homolog 1 (A. nidulans) [Source:HGNC Symbol;Acc:17619]

Coordinates

chr16:15771658-15785180:+

Coord C1 exon

chr16:15771658-15771806

Coord A exon

chr16:15781232-15781368

Coord C2 exon

chr16:15785001-15785180

Length

137 bp

Sequences

Splice sites

3' ss Seq

TCTGCTTTTCTCTTCGCCAGCGC

3' ss Score

8.04

5' ss Seq

GAGGTCAGG

5' ss Score

4.94

Exon sequences

Seq C1 exon

GAGAAGTTTGAAGTGCAGCACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGACCAAAGCCATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACGACCTGGAAAGAGCCAAGCG

Seq A exon

CGCCACGATCATGTCTCTCGAAGACTTTGAGCAGCGCTTGAATCAGGCCATCGAAAGAAATGCCTTCCTGGAAAGTGAACTTGATGAAAAAGAGAATCTCCTGGAATCTGTTCAGAGACTGAAGGATGAAGCCAGAG

Seq C2 exon

ATTTGCGGCAGGAACTGGCCGTGCAGCAGAAGCAGGAGAAACCCAGGACCCCCATGCCCAGCTCAGTGGAAGCTGAGAGGACAGACACAGCTGTGCAGGCCACGGGCTCCGTGCCGTCCACGCCCATTGCTCACCGAGGACCCAGCTCAAGTTTAAACACACCTGGGAGCTTCAGACGTG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000072864-'7-10,'7-9,8-10

Average complexity

S

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.297 A=0.394 C2=1.000

Domain overlap (PFAM):

C1:

PF0003816=Filament=PD(37.5=93.8),PF040127=PspA_IM30=PD(18.4=29.2),PF115593=ADIP=PD(22.7=45.8),PF088265=DMPK_coil=PD(1.8=2.1),PF058377=CENP-H=PD(48.8=83.3),PF039549=Lectin_N=PD(73.0=95.8),PF093045=Cortex-I_coil=PD(90.2=95.8),PF065827=DUF1136=WD(100=50.0)

A:

PF077956=DUF1635=FE(31.9=100),PF0030915=Sigma54_AID=WD(100=52.2),PF048808=NUDE_C=PU(25.6=87.0)

C2:

PF077956=DUF1635=FE(41.8=100),PF048808=NUDE_C=FE(37.8=100)

Main Inclusion Isoform:

ENSP00000379641