HsaEX0044301 @ hg19
Exon Skipping
Gene
ENSG00000095319 | NUP188
Description
nucleoporin 188kDa [Source:HGNC Symbol;Acc:17859]
Coordinates
chr9:131747179-131749154:+
Coord C1 exon
chr9:131747179-131747293
Coord A exon
chr9:131748837-131748957
Coord C2 exon
chr9:131749088-131749154
Length
121 bp
Sequences
Splice sites
3' ss Seq
CACTGCATGGTTTCTTGTAGGGG
3' ss Score
6.05
5' ss Seq
TTGGTAAGG
5' ss Score
8.92
Exon sequences
Seq C1 exon
TGCGGAAGGGATGAATGCTGGAGGGTACGGAAACCTCTTGATGAACAGTGAACAGCCTCAGGGCGAGTATGGGGTTACTATTGCCTTTCTGCGCTTGATCACCACCCTTGTCAAG
Seq A exon
GGGCAACTTGGTAGTACCCAGAGCCAAGGACTTGTACCCTGTGTAATGTTTGTGCTGAAGGAGATGCTTCCCAGCTACCATAAGTGGCGCTACAACTCTCATGGAGTGAGGGAACAGATTG
Seq C2 exon
GTTGCCTGATCTTGGAGCTGATTCATGCGATACTGAACCTGTGCCACGAGACAGACCTGCACAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095319-'25-29,'25-27,27-29
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF104874=Nup188=FE(4.1=100),PF118943=DUF3414=FE(7.7=100)
A:
PF104874=Nup188=FE(4.4=100),PF118943=DUF3414=FE(8.1=100)
C2:
PF104874=Nup188=FE(2.4=100),PF118943=DUF3414=FE(4.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGAAGGGATGAATGCTGGAG
R:
GCTGTGCAGGTCTGTCTCG
Band lengths:
178-299
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)