HsaEX0044857 @ hg19
Exon Skipping
Gene
ENSG00000184792 | OSBP2
Description
oxysterol binding protein 2 [Source:HGNC Symbol;Acc:8504]
Coordinates
chr22:31090793-31266669:+
Coord C1 exon
chr22:31090793-31091540
Coord A exon
chr22:31137148-31137356
Coord C2 exon
chr22:31266416-31266669
Length
209 bp
Sequences
Splice sites
3' ss Seq
CCTTCTCTTACATCCTACAGAAA
3' ss Score
8.49
5' ss Seq
CAGGTAGTG
5' ss Score
6.13
Exon sequences
Seq C1 exon
GAGCCCAAGCCCCAGCCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCGGAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTGTCCGAGACGACGTCTGAGCCGGAGCCAGGGGCTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGTGTAGGGGCTGGGCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAGTCAGGATCGCTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGGTTCCAATGTCGGGGACTGGCACGACCTCCAGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGGCTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGGTTCGTGCTGGGCAATGGTTTGCTCTCTTACTACAG
Seq A exon
AAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGCACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAGCTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATGAACACTCATTCAG
Seq C2 exon
ATGACTCTGGGGACGACGACGAGGCTACCACCCCAGCCGACAAGAGCGAGCTGCACCACACCCTGAAGAATCTTTCCCTGAAGTTAGATGACCTCAGCACGTGCAATGACCTCATCGCCAAGCACGGCGCTGCACTCCAGCGCTCCCTGACAGAGCTGGACGGCCTCAAGATCCCATCTGAGAGTGGGGAGAAGCTGAAGGTGGTGAATGAGCGGGCCACCCTCTTCCGCATCACATCCAATGCTATGATCAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184792-'2-14,'2-5,4-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.702 A=0.215 C2=0.233
Domain overlap (PFAM):
C1:
PF058876=Trypan_PARP=WD(100=41.9),PF0016924=PH=PU(34.1=14.4)
A:
PF154091=PH_8=PD(95.1=81.7)
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCTTCTCAAGTGGACCAAC
R:
CCGCTCATTCACCACCTTCAG
Band lengths:
298-507
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)