HsaEX0044915 @ hg38
Exon Skipping
Gene
ENSG00000070882 | OSBPL3
Description
oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370]
Coordinates
chr7:24834486-24849176:-
Coord C1 exon
chr7:24849069-24849176
Coord A exon
chr7:24842279-24842413
Coord C2 exon
chr7:24834486-24834736
Length
135 bp
Sequences
Splice sites
3' ss Seq
TGGTTTTGTTCTTCAAATAGGAA
3' ss Score
8.85
5' ss Seq
GAGGTTTGA
5' ss Score
3.11
Exon sequences
Seq C1 exon
GCCCTAGCACAAAACACAGATCTTAAAGAACGCTTACGCAGAATCCATGCCGAGTCTCTGCTCCTCGACTCCCCCGCTGTCGCCAAGTCGGGTGACAATCTGGCAGAG
Seq A exon
GAAAACTCCAGAGATGAAAACCGAGCTCTAGTTCATCAGCTTTCTAATGAAAGTAGACTCTCCATCACTGACTCCCTTTCTGAGTTTTTTGATGCTCAGGAAGTTCTGTTATCTCCAAGCTCTTCAGAAAACGAG
Seq C2 exon
GGCCTGTCCTTGATAGTGGTCGGGAAGCGAAGTCCCGGAGAAGAACGTGCCTGCCGGCGCCCTGCCCGAGCAGCAGTAACATCAGCCTGTGGAACATCCTGAGGAACAACATCGGGAAGGACCTGTCCAAGGTGGCCATGCCGGTGGAGCTGAACGAGCCCCTGAACACGCTGCAGAGGCTCTGCGAGGAGCTGGAGTACAGCGAGCTCCTGGACAAGGCCGCGCAGATTCCCAGCCCCCTGGAAAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000070882_MULTIEX1-9/21=7-12
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.244 A=0.374 C2=0.211
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0123713=Oxysterol_BP=PU(15.9=65.5)
Main Skipping Isoform:
ENST00000313367fB21721
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTACGCAGAATCCATGCCGAG
R:
GTGTTCAGGGGCTCGTTCAG
Band lengths:
244-379
Functional annotations
There are 1 annotated functions for this event
PMID: 17804640
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, confocal microscopy, cross linking study, detection by mass spectrometry, green fluorescent protein tag. ELM ID: ELMI001270; ELM sequence: DSLSEFFDAQE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development