HsaEX0044915 @ hg19
Exon Skipping
Gene
ENSG00000070882 | OSBPL3
Description
oxysterol binding protein-like 3 [Source:HGNC Symbol;Acc:16370]
Coordinates
chr7:24874105-24901388:-
Coord C1 exon
chr7:24901232-24901388
Coord A exon
chr7:24881898-24882032
Coord C2 exon
chr7:24874105-24874355
Length
135 bp
Sequences
Splice sites
3' ss Seq
TGGTTTTGTTCTTCAAATAGGAA
3' ss Score
8.85
5' ss Seq
GAGGTTTGA
5' ss Score
3.11
Exon sequences
Seq C1 exon
GTCCCGAAACCTTTTTCTGGCCCAGTAAGACTACACTCCTCCAATCCTAATTTGTCAACACTAGATTTTGGAGAAGAGAAAAATTATTCTGATGGCTCTGAAACCTCATCAGAGTTTTCTAAAATGCAAGAAGATCTGTGTCATATTGCCCATAAAG
Seq A exon
GAAAACTCCAGAGATGAAAACCGAGCTCTAGTTCATCAGCTTTCTAATGAAAGTAGACTCTCCATCACTGACTCCCTTTCTGAGTTTTTTGATGCTCAGGAAGTTCTGTTATCTCCAAGCTCTTCAGAAAACGAG
Seq C2 exon
GGCCTGTCCTTGATAGTGGTCGGGAAGCGAAGTCCCGGAGAAGAACGTGCCTGCCGGCGCCCTGCCCGAGCAGCAGTAACATCAGCCTGTGGAACATCCTGAGGAACAACATCGGGAAGGACCTGTCCAAGGTGGCCATGCCGGTGGAGCTGAACGAGCCCCTGAACACGCTGCAGAGGCTCTGCGAGGAGCTGGAGTACAGCGAGCTCCTGGACAAGGCCGCGCAGATTCCCAGCCCCCTGGAAAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000070882_MULTIEX2-3/4=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.502 A=0.369 C2=0.192
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0123713=Oxysterol_BP=PU(15.9=65.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCCGAAACCTTTTTCTGGCC
R:
ACAGGCTGATGTTACTGCTGC
Band lengths:
246-381
Functional annotations
There are 1 annotated functions for this event
PMID: 17804640
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, confocal microscopy, cross linking study, detection by mass spectrometry, green fluorescent protein tag. ELM ID: ELMI001270; ELM sequence: DSLSEFFDAQE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)