HsaEX0047880 @ hg38
Exon Skipping
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]
Coordinates
chr1:88807529-88813733:+
Coord C1 exon
chr1:88807529-88807604
Coord A exon
chr1:88807684-88807775
Coord C2 exon
chr1:88813557-88813733
Length
92 bp
Sequences
Splice sites
3' ss Seq
TTATTTTAATTTTATTTCAGGTG
3' ss Score
10.07
5' ss Seq
CAGGTTAGT
5' ss Score
8.02
Exon sequences
Seq C1 exon
ATCTCAGCAAAGGTTTCAGTTTAATCTACAAGATTTCAGGTGTTGTGCTGTCTTGGGAAGAGGACATTTTGGAAAG
Seq A exon
GTGCTTTTAGCTGAATATAAAAACACAAATGAGATGTTTGCTATAAAAGCCTTAAAGAAAGGAGATATTGTGGCTCGAGATGAAGTAGACAG
Seq C2 exon
CCTGATGTGTGAAAAAAGAATTTTTGAAACTGTGAATAGTGTAAGGCATCCCTTTTTGGTGAACCTTTTTGCATGTTTCCAAACCAAAGAGCATGTTTGCTTTGTAATGGAATATGCTGCCGGTGGGGACCTAATGATGCACATTCATACTGATGTCTTTTCTGAACCAAGAGCTGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243-'53-50,'53-47,54-50
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.008 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PU(25.0=50.0)
A:
PF0006920=Pkinase=FE(11.5=100)
C2:
PF0006920=Pkinase=FE(22.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTGTTGTGCTGTCTTGGGAA
R:
GTGCATCATTAGGTCCCCACC
Band lengths:
180-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development