HsaEX0047886 @ hg38
Exon Skipping
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]
Coordinates
chr1:88771663-88786213:+
Coord C1 exon
chr1:88771663-88771879
Coord A exon
chr1:88784639-88784824
Coord C2 exon
chr1:88786104-88786213
Length
186 bp
Sequences
Splice sites
3' ss Seq
ATATTTATGTTTGCCAACAGGTA
3' ss Score
10.07
5' ss Seq
CCAGTTCAG
5' ss Score
-14.74
Exon sequences
Seq C1 exon
GCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAGAGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAAGTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAG
Seq A exon
GTACTTTGGAAGTTCGTCTTATGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGATCATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCA
Seq C2 exon
ATGATGTCTGTGCTGTTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGGACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243_MULTIEX3-2/2=C1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.157 A=0.264 C2=0.003
Domain overlap (PFAM):
C1:
PF0218511=HR1=PD(43.8=43.8)
A:
NO
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAAGTCCCCAAGAATCATCCC
R:
CCAGTGTAAACTTCTGGTCCCA
Band lengths:
245-431
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development