HsaEX0048421 @ hg19
Exon Skipping
Gene
ENSG00000178385 | PLEKHM3
Description
pleckstrin homology domain containing, family M, member 3 [Source:HGNC Symbol;Acc:34006]
Coordinates
chr2:208773238-208811236:-
Coord C1 exon
chr2:208811091-208811236
Coord A exon
chr2:208795650-208795843
Coord C2 exon
chr2:208773238-208773301
Length
194 bp
Sequences
Splice sites
3' ss Seq
TGACGACGCTTGTTTTGTAGGTG
3' ss Score
8.36
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GCTGCCAGCGATCCATAGGTCTTTCCAATGGGAAAGCCAAGGTGTGCAACTACAGTGGGTGGTATTACTGCAGTAGCTGCCACGTGGATGACAGCTTTCTCATTCCAGCACGCATAGTCCACAACTGGGATACTTCAAAGTATAAG
Seq A exon
GTGTCGAAGCAGGCCAAGGAGTTTCTGGAGTACGTGTACGAAGAGCCGCTCATCGACATCCAGCAGGAGAACGCCATGCTGTACCACCACGCAGAGCCGCTGGCCGCCGTGCTGCGGCTGCGGCAGCGGCTGAAGTCGCTCCGAGCCTATTTGTTCAGCTGCCGGGCAGCGGTGGCAGAGGATCTCCGCCGCAG
Seq C2 exon
AATTTTCCCCAGAGAATACCTCCTTCAACAGATCCACCTGTATTCACTTGCCGACCTGCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000178385-'4-7,'4-5,5-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF139011=DUF4206=PU(19.7=71.4)
A:
PF139011=DUF4206=FE(36.0=100)
C2:
PF139011=DUF4206=FE(11.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCAGCGATCCATAGGTCTT
R:
GCAGGTCGGCAAGTGAATACA
Band lengths:
203-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)