HsaEX0048421 @ hg38
Exon Skipping
Gene
ENSG00000178385 | PLEKHM3
Description
pleckstrin homology domain containing M3 [Source:HGNC Symbol;Acc:HGNC:34006]
Coordinates
chr2:207908514-207946512:-
Coord C1 exon
chr2:207946367-207946512
Coord A exon
chr2:207930926-207931119
Coord C2 exon
chr2:207908514-207908577
Length
194 bp
Sequences
Splice sites
3' ss Seq
TGACGACGCTTGTTTTGTAGGTG
3' ss Score
8.36
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GCTGCCAGCGATCCATAGGTCTTTCCAATGGGAAAGCCAAGGTGTGCAACTACAGTGGGTGGTATTACTGCAGTAGCTGCCACGTGGATGACAGCTTTCTCATTCCAGCACGCATAGTCCACAACTGGGATACTTCAAAGTATAAG
Seq A exon
GTGTCGAAGCAGGCCAAGGAGTTTCTGGAGTACGTGTACGAAGAGCCGCTCATCGACATCCAGCAGGAGAACGCCATGCTGTACCACCACGCAGAGCCGCTGGCCGCCGTGCTGCGGCTGCGGCAGCGGCTGAAGTCGCTCCGAGCCTATTTGTTCAGCTGCCGGGCAGCGGTGGCAGAGGATCTCCGCCGCAG
Seq C2 exon
AATTTTCCCCAGAGAATACCTCCTTCAACAGATCCACCTGTATTCACTTGCCGACCTGCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000178385-'17-24,'17-20,20-24=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF139011=DUF4206=PU(17.2=71.4)
A:
PF139011=DUF4206=FE(31.4=100)
C2:
PF139011=DUF4206=FE(10.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCAGCGATCCATAGGTCTT
R:
GCAGGTCGGCAAGTGAATACA
Band lengths:
203-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development