HsaEX0050478 @ hg19
Exon Skipping
Gene
ENSG00000005001 | PRSS22
Description
protease, serine, 22 [Source:HGNC Symbol;Acc:14368]
Coordinates
chr16:2903866-2906254:-
Coord C1 exon
chr16:2906083-2906254
Coord A exon
chr16:2905575-2905852
Coord C2 exon
chr16:2903866-2904023
Length
278 bp
Sequences
Splice sites
3' ss Seq
CCCCTTCCCTTTCCTTCCAGCAA
3' ss Score
11.17
5' ss Seq
GAGGTGCGG
5' ss Score
6.79
Exon sequences
Seq C1 exon
TTCCCCCAGCCTGTGGGAAGCCCCAGCAGCTGAACCGGGTTGTGGGCGGCGAGGACAGCACTGACAGCGAGTGGCCCTGGATCGTGAGCATCCAGAAGAATGGGACCCACCACTGCGCAGGTTCTCTGCTCACCAGCCGCTGGGTGATCACTGCTGCCCACTGTTTCAAGGA
Seq A exon
CAACCTGAACAAACCATACCTGTTCTCTGTGCTGCTGGGGGCCTGGCAGCTGGGGAACCCTGGCTCTCGGTCCCAGAAGGTGGGTGTTGCCTGGGTGGAGCCCCACCCTGTGTATTCCTGGAAGGAAGGTGCCTGTGCAGACATTGCCCTGGTGCGTCTCGAGCGCTCCATACAGTTCTCAGAGCGGGTCCTGCCCATCTGCCTACCTGATGCCTCTATCCACCTCCCTCCAAACACCCACTGCTGGATCTCAGGCTGGGGGAGCATCCAAGATGGAG
Seq C2 exon
TTCCCTTGCCCCACCCTCAGACCCTGCAGAAGCTGAAGGTTCCTATCATCGACTCGGAAGTCTGCAGCCATCTGTACTGGCGGGGAGCAGGACAGGGACCCATCACTGAGGACATGCTGTGTGCCGGCTACTTGGAGGGGGAGCGGGATGCTTGTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005001_MULTIEX1-1/3=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.069 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=75.9)
A:
PF0008921=Trypsin=FE(39.4=100)
C2:
PF0008921=Trypsin=FE(22.0=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCCCCAGCAGCTGAAC
R:
CTCCAAGTAGCCGGCACAC
Band lengths:
293-571
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)