HsaINT0132954 @ hg19
Intron Retention
Gene
ENSG00000005001 | PRSS22
Description
protease, serine, 22 [Source:HGNC Symbol;Acc:14368]
Coordinates
chr16:2905575-2906254:-
Coord C1 exon
chr16:2906083-2906254
Coord A exon
chr16:2905853-2906082
Coord C2 exon
chr16:2905575-2905852
Length
230 bp
Sequences
Splice sites
5' ss Seq
GGAGTATGT
5' ss Score
4.82
3' ss Seq
CCCCTTCCCTTTCCTTCCAGCAA
3' ss Score
11.17
Exon sequences
Seq C1 exon
TTCCCCCAGCCTGTGGGAAGCCCCAGCAGCTGAACCGGGTTGTGGGCGGCGAGGACAGCACTGACAGCGAGTGGCCCTGGATCGTGAGCATCCAGAAGAATGGGACCCACCACTGCGCAGGTTCTCTGCTCACCAGCCGCTGGGTGATCACTGCTGCCCACTGTTTCAAGGA
Seq A exon
GTATGTACAGCCGGCCTGGGGCACTTGATCTTCTAAGGCCCTGGGCTTTGTGCCCCAGGCCCTGGGCTCCCTTTACAGGCTCTGCTTCCGGGCCTCTGTTCAATCTTGGTGCCCCTCGATTCTACCTAGAAGCCTCTCCTGCCTTCAGGGGCCTTCACACCCATGCTGTTCCCCCAGGTACCTCCTCCCAGACCAGGCCTGGCTGATCCTCCCCTTCCCTTTCCTTCCAG
Seq C2 exon
CAACCTGAACAAACCATACCTGTTCTCTGTGCTGCTGGGGGCCTGGCAGCTGGGGAACCCTGGCTCTCGGTCCCAGAAGGTGGGTGTTGCCTGGGTGGAGCCCCACCCTGTGTATTCCTGGAAGGAAGGTGCCTGTGCAGACATTGCCCTGGTGCGTCTCGAGCGCTCCATACAGTTCTCAGAGCGGGTCCTGCCCATCTGCCTACCTGATGCCTCTATCCACCTCCCTCCAAACACCCACTGCTGGATCTCAGGCTGGGGGAGCATCCAAGATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005001-PRSS22:NM_022119:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.069 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=75.9)
A:
NA
C2:
PF0008921=Trypsin=FE(39.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAGAATGGGACCCACCACT
R:
GGGAGGTGGATAGAGGCATCA
Band lengths:
307-537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)