HsaEX0050478 @ hg38
Exon Skipping
Gene
ENSG00000005001 | PRSS22
Description
protease, serine 22 [Source:HGNC Symbol;Acc:HGNC:14368]
Coordinates
chr16:2853865-2856253:-
Coord C1 exon
chr16:2856082-2856253
Coord A exon
chr16:2855574-2855851
Coord C2 exon
chr16:2853865-2854022
Length
278 bp
Sequences
Splice sites
3' ss Seq
CCCCTTCCCTTTCCTTCCAGCAA
3' ss Score
11.17
5' ss Seq
GAGGTGCGG
5' ss Score
6.79
Exon sequences
Seq C1 exon
TTCCCCCAGCCTGTGGGAAGCCCCAGCAGCTGAACCGGGTTGTGGGCGGCGAGGACAGCACTGACAGCGAGTGGCCCTGGATCGTGAGCATCCAGAAGAATGGGACCCACCACTGCGCAGGTTCTCTGCTCACCAGCCGCTGGGTGATCACTGCTGCCCACTGTTTCAAGGA
Seq A exon
CAACCTGAACAAACCATACCTGTTCTCTGTGCTGCTGGGGGCCTGGCAGCTGGGGAACCCTGGCTCTCGGTCCCAGAAGGTGGGTGTTGCCTGGGTGGAGCCCCACCCTGTGTATTCCTGGAAGGAAGGTGCCTGTGCAGACATTGCCCTGGTGCGTCTCGAGCGCTCCATACAGTTCTCAGAGCGGGTCCTGCCCATCTGCCTACCTGATGCCTCTATCCACCTCCCTCCAAACACCCACTGCTGGATCTCAGGCTGGGGGAGCATCCAAGATGGAG
Seq C2 exon
TTCCCTTGCCCCACCCTCAGACCCTGCAGAAGCTGAAGGTTCCTATCATCGACTCGGAAGTCTGCAGCCATCTGTACTGGCGGGGAGCAGGACAGGGACCCATCACTGAGGACATGCTGTGTGCCGGCTACTTGGAGGGGGAGCGGGATGCTTGTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005001-'9-10,'9-7,13-10
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.076 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=75.9)
A:
PF0008921=Trypsin=FE(39.4=100)
C2:
PF0008921=Trypsin=FE(22.0=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCCCCAGCAGCTGAAC
R:
CTCCAAGTAGCCGGCACAC
Band lengths:
293-571
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development