HsaINT0132955 @ hg38
Intron Retention
Gene
ENSG00000005001 | PRSS22
Description
protease, serine 22 [Source:HGNC Symbol;Acc:HGNC:14368]
Coordinates
chr16:2853865-2855851:-
Coord C1 exon
chr16:2855574-2855851
Coord A exon
chr16:2854023-2855573
Coord C2 exon
chr16:2853865-2854022
Length
1551 bp
Sequences
Splice sites
5' ss Seq
GAGGTGCGG
5' ss Score
6.79
3' ss Seq
TCTGTCCTCTTTCCTCCCAGTTC
3' ss Score
10.92
Exon sequences
Seq C1 exon
CAACCTGAACAAACCATACCTGTTCTCTGTGCTGCTGGGGGCCTGGCAGCTGGGGAACCCTGGCTCTCGGTCCCAGAAGGTGGGTGTTGCCTGGGTGGAGCCCCACCCTGTGTATTCCTGGAAGGAAGGTGCCTGTGCAGACATTGCCCTGGTGCGTCTCGAGCGCTCCATACAGTTCTCAGAGCGGGTCCTGCCCATCTGCCTACCTGATGCCTCTATCCACCTCCCTCCAAACACCCACTGCTGGATCTCAGGCTGGGGGAGCATCCAAGATGGAG
Seq A exon
GTGCGGCTTCTTCCTCTCCAAGGTGGTTGGGGGCAGATGGGGACAGAGGATGGCAGACACTCAGGGACACAGACACCATGAGCAACAAAGGGTGGAGGCCAGAGGCACAGCATGACAGAGGTGGAAGGAAAGATGGGCTGCAATCCAGAAGAAACCTTGGTGGGCAATTTCAGGCCATTTCTCTTTTCTTTTCTTTCTTCTTCTTCTTTTTTTTTTTTTTTTTTTTGAGACAGGGTGTTACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCCTAACTCACTGCAGCCTTTGCCTCCCAGGCTCAAGTGATCCTCCCACCTCAGCCTCCCAGGTAGCTGGAACTACAGGTGTGTGCTACCACACCTGGCTAATTTTTGTATTTTTTGTAGAGACAGGGTTTTTCTGTGTTGGCTGGGCTGGTCTTGAACTGTTGGGCTCAAGCAATCCACCAGCCTCAGCCTCCCAAAGTGCCGGGATTACAGGTGTGAGCCACTGTGCCTGGCCTCATTTCTACTTCAAAAGTATCTGGCTATGTTTTGAGGCAACAGCCAGACCCGTGAAGCTATTCAATTCATCAATACAGGAATGGCTGAAAGGGGGTGTGTGTGGGACTAAGCTGAATACAGGGTGAATATAAAGAGGCCTGATTCCAGAGTGGGAACAGGCACCCCCTGGTGGTAGCATGCCACAATTGCGGGCAAAATTCTCGGGAGAAAATGCAGCCACCTTAATTGTAAAATATAATTTTCAAACCACCACTGGAGGTTTGGAAAACATCATCTCAAAACTCAAACTAGATTACATAAAGCAAGAAGCAGGGAAGCAGCAAGAGAAAGGTAGATGACAGATCGACAGGCAGATGGATGATAGAGACTGGGCCAAGGAAAAGAAACATACAGGCAGAAATGAGGATACAATGAAGACCTGGAAGAAAGAGTTTGAAAGAGAGAGCTAGAGACTAAGTAATAACAAAGTGTAAGACAGATGAAAATTTAACCAGATTCCAGAATAATTAAGAGAAATGACACTAGCTCAGGTGTGTGGGGATCCCAGTAACTCTGAGGTTGCAACCTCTCCATGATCTCTGTAGGGGCTTCTTCAAGAGCTAGAATCGCGGACTTTCAGTCCACAATCTGCAGACCACAGTCTGTAGACCAGCTCCAGGCAAGGCGTGGGGATCCCTCAGGTCCTGGTAATTTTCAACATCGAGTGGACATTTATTGAACACTTCTTCTATAGCAGTCCCAGTGCTGGATGAAGTAATGCAGTATCTGAGACAGGAAGGGCTCTAACCATCTGTGGATATAAGAAAATTTATTAAAGAGGTAGGGTCTTAGGTTTCACATTCATGTTCTAATTCAGCAGGGCCAGAGGTGGAGACCTGGAATTTCAATTTTCTGAAGGCATCTTGGGAGAGACTGGTAGAGCTAATCTGTTAGCCTTTGAGAACCGCTGCTGAGAGGAATGGTGTTGGGGGGGAATAGTCCTTTGAGGAGGCAACGAGGAGGGGAGACCCCCAAACCTGATTCTGTCCTCTTTCCTCCCAG
Seq C2 exon
TTCCCTTGCCCCACCCTCAGACCCTGCAGAAGCTGAAGGTTCCTATCATCGACTCGGAAGTCTGCAGCCATCTGTACTGGCGGGGAGCAGGACAGGGACCCATCACTGAGGACATGCTGTGTGCCGGCTACTTGGAGGGGGAGCGGGATGCTTGTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005001:ENST00000161006:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.4=100)
A:
NA
C2:
PF0008921=Trypsin=FE(22.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCTGTTCTCTGTGCTGCTG
R:
CCAGTACAGATGGCTGCAGAC
Band lengths:
342-1893
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development