HsaEX0055737 @ hg19
Exon Skipping
Gene
ENSG00000124782 | RREB1
Description
ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:10449]
Coordinates
chr6:7240671-7249507:+
Coord C1 exon
chr6:7240671-7240835
Coord A exon
chr6:7246657-7247454
Coord C2 exon
chr6:7248744-7249507
Length
798 bp
Sequences
Splice sites
3' ss Seq
CCGCTGTGCTTGCCCCACAGACA
3' ss Score
10.27
5' ss Seq
CAGGTAACC
5' ss Score
8.66
Exon sequences
Seq C1 exon
GTCAGAAACCCTTCCCTTGTCAAAAATGCGATGCCTTCTTTTCTACCAAATCTAACTGTGAACGCCACCAGTTGCGCAAACACGGAGTTACCACCTGTTCCCTGAGAAGAAACGGGCTTATCCCCCAGTCAAAAGAGAGTGATGTTGGATCCCATGATAGCACAG
Seq A exon
ACAGTCAGTCGGATGCGGAGACTGCAGCCGCCGCGGGCGAAGTGCTAGACCTCACCTCACGGGACAGAGAGCAGCCGTCGGAGGGCGCCACTGAGCTCCGCCAGGTCGCAGGGGATGCGCCTGTGGAGCAGGCCACGGCGGAAACGGCCTCGCCGGTGCACCGGGAAGAGCACGGGCGTGGGGAGAGCCATGAGCCGGAGGAGGAGCATGGCACTGAGGAGAGCACTGGGGACGCCGACGGCGCGGAAGAGGACGCGTCGAGCAACCAGAGCCTGGACCTGGACTTCGCCACCAAGCTCATGGACTTCAAGCTGGCGGAGGGCGACGGCGAGGCAGGCGCCGGGGGCGCGGCCTCGCAGGAGCAGAAGCTCGCCTGCGACACCTGTGGGAAGAGCTTCAAGTTCCTGGGCACCCTGAGCCGCCACCGGAAGGCGCACGGCCGCCAGGAGCCCAAGGACGAGAAGGGAGATGGCGCCAGCACTGCAGAGGAGGGGCCCCAGCCCGCCCCTGAACAGGAGGAGAAGCCCCCCGAGACCCCGGCAGAGGTGGTGGAGTCGGCCCCGGGTGCCGGGGAGGCCCCGGCGGAAAAGCTCGCGGAGGAGACGGAGGGCCCCTCCGACGGGGAGAGCGCGGCCGAGAAAAGGTCCTCAGAGAAGAGCGACGATGACAAGAAACCAAAGACAGACTCCCCCAAAAGCGTGGCCAGCAAGGCAGACAAGAGGAAGAAGGTCTGCAGCGTGTGCAACAAGCGGTTCTGGTCGCTGCAGGACCTGACCCGGCACATGCGCTCCCACACAG
Seq C2 exon
GGGAAAGGCCATACAAATGTCAGACCTGCGAGCGAACCTTCACCTTGAAGCACAGCCTGGTTCGCCACCAGCGGATCCACCAGAAAGCCAGGCATGCCAAACACCACGGGAAGGACAGCGACAAGGAAGAGCGGGGTGAGGAGGACAGCGAGAATGAGTCCACCCACAGCGGCAACAACGCCGTCTCAGAGAACGAGGCTGAGCTGGCTCCCAATGCCAGCAACCACATGGCTGTCACCCGGAGCCGGAAGGAGGGCTTGGCCAGTGCCACCAAGGACTGCAGCCACAGGGAGGAGAAGGTCACGGCAGGGTGGCCGTCTGAGCCTGGCCAGGGTGACCTTAACCCAGAGAGCCCGGCGGCCCTGGGGCAGGACCTGCTGGAGCCGCGCAGCAAGAGGCCTGCCCACCCAATCCTGGCCACAGCTGATGGCGCCTCCCAGCTCGTGGGGATGGAGTGACAGCCTCAGTCCCCCTCAGCACAGACAAAAGCCAGCAGAGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124782-'31-36,'31-29,39-36
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=0.916 C2=0.935
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PD(57.7=26.8)
A:
PF0009621=zf-C2H2=WD(100=8.6),PF134651=zf-H2C2_2=PU(40.0=3.7)
C2:
PF134651=zf-H2C2_2=PD(56.0=9.2)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTTGTCAAAAATGCGATGCC
R:
GTTCTCTGAGACGGCGTTGTT
Band lengths:
346-1144
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)