HsaEX0056667 @ hg19
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain, EGF-like 2 [Source:HGNC Symbol;Acc:30425]
Coordinates
chr11:9052305-9069109:-
Coord C1 exon
chr11:9068903-9069109
Coord A exon
chr11:9055173-9055343
Coord C2 exon
chr11:9052305-9052472
Length
171 bp
Sequences
Splice sites
3' ss Seq
GTTGTTTCCCTTTTGGCTAGTCA
3' ss Score
4.33
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
CTTCTTGTGACCTGAGCTGCATCGTAAAGCGAACCGAGAAGCGGCTCCGTAAAGCCATCCGCACGCTCAGAAAGGCCGTCCACAGGGAGCAGTTTCACCTCCAGCTCTCAGGCATGAACCTCGACGTGGCTAAAAAGCCTCCCAGAACATCTGAACGCCAGGCAGAGTCCTGTGGAGTGGGCCAGGGTCATGCAGAAAACCAATGTG
Seq A exon
TCAGTTGCAGGGCTGGGACCTATTATGATGGAGCACGAGAACGCTGCATTTTATGTCCAAATGGAACCTTCCAAAATGAGGAAGGACAAATGACTTGTGAACCATGCCCAAGACCAGGAAATTCTGGGGCCCTGAAGACCCCAGAAGCTTGGAATATGTCTGAATGTGGAG
Seq C2 exon
GTCTGTGTCAACCTGGTGAATATTCTGCAGATGGCTTTGCACCTTGCCATCTCTGTGCCCTGGGCACGTTCCAGCCTGAAGCTGGTCGAACTTCCTGCTTCCCCTGTGGAGGAGGCCTTGCCACCAAACATCAGGGAGCTACTTCCTTTCAGGACTGTGAAACCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.310 A=0.034 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF076998=GCC2_GCC3=WD(100=87.9),PF075629=NCD3G=WD(100=46.6)
C2:
PF076998=GCC2_GCC3=WD(100=84.2)
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGTTTCACCTCCAGCTCTC
R:
TCCCTGATGTTTGGTGGCAAG
Band lengths:
256-427
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)